Management of 201 individuals with emotionally unstable personality disorders: A naturalistic observational study in real-world inpatient setting.

Pub Date : 2021-07-01
Homayun Shahpesandy, Rosemary Mohammed-Ali, Michael Oakes, Tarik Al-Kubaisy, Anna Cheetham, Moses Anene
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Abstract

Background: Emotionally unstable personality disorder (EUPD) is a challenging condition with a prevalence of 20% in inpatient services. Psychotherapy is the preferred treatment; nevertheless, off-license medications are widely used.

Objectives: To identify socio-demographics, clinical and service-delivery characteristics of people with EUPD admitted to inpatient services between 1st January 2017 and 31st December 2018.

Methods: A retrospective review using data from patients' records. Individuals, age 18-65 were included. Statistical analysis was conducted by the Mann-Whitney-Wilcoxon test and Chi-squared test with Yates's continuity correction.

Results: Of 1646 inpatients, 201 (12.2%); had the diagnosis of EUPD; 133 (66.0%) women, 68 (44.0%). EUPD was significantly (P < .001) more prevalent in women (18.2%) than men (7.4%). EUPD patients were significantly (P < .001) younger (32.2 years) than patients without EUPD (46 years), and had significantly (P < .001) more admissions (1.74) than patients without EUPD (1.2 admission). 70.5% of patients had one and 17.0% two Axis-I psychiatric co-morbidities. Substance use was significantly (P < .001) more often in men (57.3%) than in women (28.5%). Significantly (P = 0.047) more women (68.4%) than men (53.0%) reported sexual abuse. 87.5% used polypharmacy. Antidepressants were significantly (P = 0.02) often prescribed to women (76.6%) than men (69.1%). Significantly (P = 0.02) more women (83.5%) than men (67.6%) were on antipsychotics. 57.2% of the patients were on anxiolytics, 40.0% on hypnotics and 25.8% on mood stabilisers.

Conclusion: EUPD is a complex condition with widespread comorbidity. The term EUPD, Borderline Personality Disorder is unsuitable, stigmatising and too simplistic to reflect the nature, gravity and psychopathology of this syndrome.

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201例情绪不稳定型人格障碍患者的管理:现实世界住院环境中的自然主义观察研究。
背景:情绪不稳定型人格障碍(EUPD)是一种具有挑战性的疾病,在住院服务中患病率为20%。心理治疗是首选的治疗方法;然而,未经许可的药物被广泛使用。目的:确定2017年1月1日至2018年12月31日住院的EUPD患者的社会人口统计学、临床和服务提供特征。方法:回顾性分析患者病历资料。包括18-65岁的个体。统计分析采用Mann-Whitney-Wilcoxon检验和卡方检验,并采用Yates连续性校正。结果:1646例住院患者中,201例(12.2%);诊断为EUPD;女性133例(66.0%),68例(44.0%)。EUPD在女性中的患病率(18.2%)明显高于男性(7.4%)(P < 0.001)。EUPD患者(32.2岁)明显(P < 0.001)低于无EUPD患者(46岁),且明显(P < 0.001)低于无EUPD患者(46岁)。“边缘型人格障碍”(EUPD)一词并不合适,带有污名性,而且过于简单,无法反映这种综合征的性质、严重性和精神病理学。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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