Biological Importance, Therapeutic Benefit and Analytical Aspects of Bioactive Flavonoid Pectolinarin in the Nature.

Dinesh K Patel
{"title":"Biological Importance, Therapeutic Benefit and Analytical Aspects of Bioactive Flavonoid Pectolinarin in the Nature.","authors":"Dinesh K Patel","doi":"10.2174/1872312814666210726112910","DOIUrl":null,"url":null,"abstract":"<p><strong>Backgrounds: </strong>Plants and their derived products have been used in the traditional system of medicine for the treatment of various forms of human disorders since very ancient times. In the traditional system of medicine and modern allopathic medicine, numerous phytoconstituents have been used for the preparation of various types of formulation. Flavonoidal class phytochemicals are the main active phytoconstituents of plants, fruit, vegetables and beverages. Flavonoidal class phytochemicals are more referred as \"nutraceuticals\" due to their important pharmacological activities in the mammalian body.</p><p><strong>Methods: </strong>In order to understand the beneficial health effects of flavonoidal class chemical, the present work summarized the health beneficial aspects of pectolinarin. Present work summarized the medicinal importance, pharmacological activities and analytical aspects of pectolinarin with various experimental models and advance analytical methods. However, all the collected scientific information's have been analyzed in the present work for their health beneficial potential.</p><p><strong>Results: </strong>From the analysis of all the collected scientific information in the present work, it was found that pectolinarin is an important phytochemical present in numerous medicinal plants but especially found in Cirsium japonicum, which is an important medicinal herb of Korea, China and Japan. Pharmacological activities data analysis signified the health beneficial potential of pectolinarin for their anti-rheumatoid arthritis, analgesic, anti-inflammatory, hepatoprotective, anti-diabetic, anti-tumor, anti-dengue, antiviral, neuroprotective and antidepressant activity. However, the effectiveness of pectolinarin in central nervous system, bone, liver and cancerous disorders have been also reported in the literature. Analysis of present scientific information revealed the health beneficial potential of pectolinarin in modern medicine due to their numerous pharmacological activities in different parts of biological systems. Due to their biological importance in food and human health, a better understanding of their biological activities indicates their potentials as therapeutic agents.</p><p><strong>Conclusion: </strong>Scientific data of the present work signified the biological potential and therapeutic benefit of pectolinarin.</p>","PeriodicalId":11339,"journal":{"name":"Drug metabolism letters","volume":"14 2","pages":"117-125"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Drug metabolism letters","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1872312814666210726112910","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2

Abstract

Backgrounds: Plants and their derived products have been used in the traditional system of medicine for the treatment of various forms of human disorders since very ancient times. In the traditional system of medicine and modern allopathic medicine, numerous phytoconstituents have been used for the preparation of various types of formulation. Flavonoidal class phytochemicals are the main active phytoconstituents of plants, fruit, vegetables and beverages. Flavonoidal class phytochemicals are more referred as "nutraceuticals" due to their important pharmacological activities in the mammalian body.

Methods: In order to understand the beneficial health effects of flavonoidal class chemical, the present work summarized the health beneficial aspects of pectolinarin. Present work summarized the medicinal importance, pharmacological activities and analytical aspects of pectolinarin with various experimental models and advance analytical methods. However, all the collected scientific information's have been analyzed in the present work for their health beneficial potential.

Results: From the analysis of all the collected scientific information in the present work, it was found that pectolinarin is an important phytochemical present in numerous medicinal plants but especially found in Cirsium japonicum, which is an important medicinal herb of Korea, China and Japan. Pharmacological activities data analysis signified the health beneficial potential of pectolinarin for their anti-rheumatoid arthritis, analgesic, anti-inflammatory, hepatoprotective, anti-diabetic, anti-tumor, anti-dengue, antiviral, neuroprotective and antidepressant activity. However, the effectiveness of pectolinarin in central nervous system, bone, liver and cancerous disorders have been also reported in the literature. Analysis of present scientific information revealed the health beneficial potential of pectolinarin in modern medicine due to their numerous pharmacological activities in different parts of biological systems. Due to their biological importance in food and human health, a better understanding of their biological activities indicates their potentials as therapeutic agents.

Conclusion: Scientific data of the present work signified the biological potential and therapeutic benefit of pectolinarin.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
天然生物活性类黄酮Pectolinarin的生物学意义、治疗效益及分析方面。
背景:植物及其衍生产品自古以来就在传统医学体系中用于治疗各种形式的人类疾病。在传统医学和现代对抗医学体系中,许多植物成分已被用于制备各种类型的制剂。黄酮类植物化学物质是植物、水果、蔬菜和饮料中的主要活性植物成分。由于黄酮类植物化学物质在哺乳动物体内具有重要的药理活性,因此更被称为“营养保健品”。方法:为了解黄酮类化学物质的有益保健作用,本文对麝香树苷的有益保健方面进行了综述。本文综述了pectolinarin的药用价值、药理活性和分析方面,并介绍了各种实验模型和最新的分析方法。然而,在目前的工作中,所有收集到的科学信息都被分析了它们的健康益处潜力。结果:通过对收集到的所有科学资料的分析,发现pectolinarin是一种重要的植物化学物质,存在于许多药用植物中,特别是在朝鲜,中国和日本的重要草药Cirsium japonicum中。药理活性数据分析表明,pectolinarin具有抗类风湿关节炎、镇痛、抗炎、保肝、抗糖尿病、抗肿瘤、抗登革热、抗病毒、神经保护和抗抑郁活性。然而,pectolinarin在中枢神经系统,骨骼,肝脏和癌症疾病中的有效性也有文献报道。对现有科学信息的分析显示,由于其在生物系统不同部位的众多药理活性,pectolinarin在现代医学中具有有益健康的潜力。由于它们在食品和人类健康中的生物学重要性,更好地了解它们的生物活性表明它们作为治疗剂的潜力。结论:本工作的科学数据表明了pectolinarin的生物学潜力和治疗价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Drug metabolism letters
Drug metabolism letters Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
自引率
0.00%
发文量
12
期刊介绍: Drug Metabolism Letters publishes letters and research articles on major advances in all areas of drug metabolism and disposition. The emphasis is on publishing quality papers very rapidly by taking full advantage of the Internet technology both for the submission and review of manuscripts. The journal covers the following areas: In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites.
期刊最新文献
The role of plant-based products in the prevention of neurological complications. The Impact of the Coronavirus (COVID-19) Infection on the Drug-Metabolizing Enzymes Cytochrome P450s. ZY12201, A Potent TGR5 Agonist: Identification of a Novel Pan CYP450 Inhibitor Tool Compound for In-Vitro Assessment. Meet the Editorial Board Member Assessment of Prescribability and Switchability by Using Multiple Bioequivalence Assessment Approaches.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1