Does the extent of soft tissue dissection and location of screws in anterior cervical discectomy and fusion impact the development of the adjacent segment degeneration? A prospective short-term radiological analysis.

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-04-01 Epub Date: 2021-08-03 DOI:10.23736/S0390-5616.21.05458-8
Mudumba Vijaya Saradhi, Kode Sashanka, Rajesh Alugolu
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Abstract

Background: Cervical degenerative disc disease is a common condition in neurosurgical practice. Elimination of a motion segment through fusion causes the load shift to the adjacent levels leading to disc degeneration. Our hypothesis is that by avoiding excessive dissection of the prevertebral soft tissue and placing anchoring screws away the adjacent endplate, we can reduce the load bearing and degeneration rate.

Methods: This is a prospective randomized control study. The study included 30 consecutive cases requiring single level ACDF, 15 each in conservative and minimal dissection group. MRI evidence of disc degeneration was assessed according to Matsumoto MRI grading system.

Results: No significant role of age on ASD was noted (P=0.26). ASD was worse in females than males especially at the inferior level (P=0.035). ASD was noted to be higher when the patients were operated at C5-6 level (P=0.026). The reduction in VAS was 5.933 in the minimal dissection group which was significantly better than the conventional surgery group (5.14) (P=0.023). The increase in degeneration score was 0.97 and 0.6 at superior and inferior levels, respectively, in the conventional group and 0.13 and 0.34 in minimal dissection group.

Conclusions: The minimal soft tissue dissection for single level ACDF with PEEK cage placement appears to have reducing rate of ASD compared to conventional ACDF. Minimal soft tissue dissection has better postoperative VAS scores.

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颈椎椎间盘切除前路融合术中软组织剥离的范围和螺钉的位置会影响邻近节段退变的发展吗?一项前瞻性短期放射学分析。
背景:颈椎间盘退行性病变是神经外科的常见病。通过融合消除运动节段会导致负荷转移到邻近水平,从而导致椎间盘退变。我们的假设是,通过避免过度剥离椎体前软组织并将锚定螺钉放置在远离邻近终板的位置,可以减少负荷和退变率:这是一项前瞻性随机对照研究,共纳入 30 例需要单水平 ACDF 的连续病例,保守组和最小剥离组各 15 例。根据松本磁共振成像分级系统评估椎间盘退变的磁共振成像证据:结果:年龄对 ASD 没有明显影响(P-0.26)。女性的 ASD 比男性严重,尤其是在下水平(P- 0.035)。在C5-6水平手术的患者ASD更高(P-0.026)。最小剥离组的 VAS 下降率为 5.933,明显优于传统手术组(5.14)(P-0.023)。传统手术组上、下水平的退化评分分别增加了 0.97 和 0.6,而最小剥离组分别增加了 0.13 和 0.34:与传统的 ACDF 相比,单水平 ACDF 的最小软组织剥离和 PEEK 骨笼置入似乎可降低 ASD 的发生率。最小软组织剥离组的术后 VAS 评分更高。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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