Prevalence of dog-mediated rabies in Ethiopia: a systematic review and Meta-analysis from 2010 to 2020.

Shiret Belete, Melke Meseret, Haileyesus Dejene, Ayalew Assefa
{"title":"Prevalence of dog-mediated rabies in Ethiopia: a systematic review and Meta-analysis from 2010 to 2020.","authors":"Shiret Belete, Melke Meseret, Haileyesus Dejene, Ayalew Assefa","doi":"10.1186/s42522-021-00046-7","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Ethiopia accommodates the second largest number of human rabies deaths in Africa. This systematic review and meta-analysis aimed to summarize and pool estimates of dog-mediated rabies status in Ethiopia.</p><p><strong>Methods: </strong>Published researches between 2010 and 2020 were comprehensively searched and the required information was extracted. The prevalence was estimated using the random-effects meta-analysis because higher heterogeneity between studies was expected.</p><p><strong>Results: </strong>The pooled estimate of rabies was 32% (95% CI: 19-46%), with individual study prevalence estimates ranged from 1 to 78%. Studies were approximately weighted equally with individual weight ranging from 5.19-5.28%. Subgroup analysis indicated that the random pooled prevalence of rabies was 28% (95% CI: 0-81%) in animals and 33% (95% CI: 20-47%) in humans. Furthermore, a subgroup analysis across regions indicated that the pooled prevalence was 78% in Addis Ababa, 46% in Oromia, 40% in Tigray and 5% in Amhara regional states. No single study was reported from the country's eastern and southern parts to be included in this meta-analysis.</p><p><strong>Conclusion: </strong>The estimated pooled rabies prevalence was found high and showed varying among study regions. Therefore, focusing on mass dog vaccination campaigns and public awareness should be implemented to control the disease.</p>","PeriodicalId":19490,"journal":{"name":"One Health Outlook","volume":"3 1","pages":"16"},"PeriodicalIF":0.0000,"publicationDate":"2021-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336362/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"One Health Outlook","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s42522-021-00046-7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Ethiopia accommodates the second largest number of human rabies deaths in Africa. This systematic review and meta-analysis aimed to summarize and pool estimates of dog-mediated rabies status in Ethiopia.

Methods: Published researches between 2010 and 2020 were comprehensively searched and the required information was extracted. The prevalence was estimated using the random-effects meta-analysis because higher heterogeneity between studies was expected.

Results: The pooled estimate of rabies was 32% (95% CI: 19-46%), with individual study prevalence estimates ranged from 1 to 78%. Studies were approximately weighted equally with individual weight ranging from 5.19-5.28%. Subgroup analysis indicated that the random pooled prevalence of rabies was 28% (95% CI: 0-81%) in animals and 33% (95% CI: 20-47%) in humans. Furthermore, a subgroup analysis across regions indicated that the pooled prevalence was 78% in Addis Ababa, 46% in Oromia, 40% in Tigray and 5% in Amhara regional states. No single study was reported from the country's eastern and southern parts to be included in this meta-analysis.

Conclusion: The estimated pooled rabies prevalence was found high and showed varying among study regions. Therefore, focusing on mass dog vaccination campaigns and public awareness should be implemented to control the disease.

Abstract Image

Abstract Image

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
埃塞俄比亚犬媒狂犬病流行情况:2010 年至 2020 年系统回顾和元分析。
背景:埃塞俄比亚是非洲人类狂犬病死亡人数第二多的国家。本系统综述和荟萃分析旨在总结和汇集埃塞俄比亚由犬介导的狂犬病状况的估计值:全面检索了 2010 年至 2020 年间发表的研究报告,并提取了所需信息。由于预计研究之间的异质性较高,因此采用随机效应荟萃分析法估算患病率:狂犬病的汇总估计值为 32%(95% CI:19-46%),单个研究的流行率估计值介于 1% 与 78% 之间。各项研究的权重大致相当,单项权重在 5.19-5.28% 之间。分组分析表明,狂犬病的随机汇总流行率在动物中为 28%(95% CI:0-81%),在人类中为 33%(95% CI:20-47%)。此外,跨地区分组分析表明,亚的斯亚贝巴的综合发病率为 78%,奥罗莫州为 46%,提格雷州为 40%,阿姆哈拉州为 5%。该国东部和南部地区没有任何研究报告被纳入此次荟萃分析:结论:经汇总的狂犬病发病率估计值较高,且各研究地区之间存在差异。因此,应重点开展大规模的狗疫苗接种活动和提高公众意识,以控制狂犬病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Global One Health post-graduate programmes: a review The impact of controlling diseases of significant global importance on greenhouse gas emissions from livestock production The One Health High-Level Expert Panel (OHHLEP) Drug resistance and extended-spectrum β-lactamase (ESBLs) - producing Enterobacteriaceae, Acinetobacter and Pseudomonas species from the views of one-health approach in Ethiopia: a systematic review and meta-analysis. Pillars for successful operationalization of one health as an ecosystem approach: experience from a human-animal interface in the Maasai steppe in Tanzania.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1