{"title":"Validating Sequence Analysis Typologies Using Parametric Bootstrap.","authors":"Matthias Studer","doi":"10.1177/00811750211014232","DOIUrl":null,"url":null,"abstract":"<p><p>In this article, the author proposes a methodology for the validation of sequence analysis typologies on the basis of parametric bootstraps following the framework proposed by Hennig and Lin (2015). The method works by comparing the cluster quality of an observed typology with the quality obtained by clustering similar but nonclustered data. The author proposes several models to test the different structuring aspects of the sequences important in life-course research, namely, sequencing, timing, and duration. This strategy allows identifying the key structural aspects captured by the observed typology. The usefulness of the proposed methodology is illustrated through an analysis of professional and coresidence trajectories in Switzerland. The proposed methodology is available in the WeightedCluster R library.</p>","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":" ","pages":"290-318"},"PeriodicalIF":4.7000,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bc/25/10.1177_00811750211014232.PMC8314995.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"90","ListUrlMain":"https://doi.org/10.1177/00811750211014232","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/6/14 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
引用次数: 0
Abstract
In this article, the author proposes a methodology for the validation of sequence analysis typologies on the basis of parametric bootstraps following the framework proposed by Hennig and Lin (2015). The method works by comparing the cluster quality of an observed typology with the quality obtained by clustering similar but nonclustered data. The author proposes several models to test the different structuring aspects of the sequences important in life-course research, namely, sequencing, timing, and duration. This strategy allows identifying the key structural aspects captured by the observed typology. The usefulness of the proposed methodology is illustrated through an analysis of professional and coresidence trajectories in Switzerland. The proposed methodology is available in the WeightedCluster R library.
期刊介绍:
ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications.
The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.