Validating Sequence Analysis Typologies Using Parametric Bootstrap.

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2021-08-01 Epub Date: 2021-06-14 DOI:10.1177/00811750211014232
Matthias Studer
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Abstract

In this article, the author proposes a methodology for the validation of sequence analysis typologies on the basis of parametric bootstraps following the framework proposed by Hennig and Lin (2015). The method works by comparing the cluster quality of an observed typology with the quality obtained by clustering similar but nonclustered data. The author proposes several models to test the different structuring aspects of the sequences important in life-course research, namely, sequencing, timing, and duration. This strategy allows identifying the key structural aspects captured by the observed typology. The usefulness of the proposed methodology is illustrated through an analysis of professional and coresidence trajectories in Switzerland. The proposed methodology is available in the WeightedCluster R library.

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使用参数引导法验证序列分析类型。
在本文中,作者按照 Hennig 和 Lin(2015 年)提出的框架,提出了一种基于参数引导的序列分析类型学验证方法。该方法通过比较观察到的类型学的聚类质量与通过聚类相似但未聚类的数据所获得的质量。作者提出了几个模型来测试生命历程研究中重要的序列的不同结构方面,即排序、时间和持续时间。通过这一策略,可以确定观察到的类型所反映的关键结构方面。通过对瑞士的职业轨迹和同居轨迹的分析,说明了所建议方法的实用性。建议的方法可在 WeightedCluster R 库中找到。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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