Musculoskeletal Disorders and Associated Factors Among Patients with Chronic Kidney Disease Attending at Saint Paul Hospital, Addis Ababa, Ethiopia.

IF 2.1 Q2 UROLOGY & NEPHROLOGY International Journal of Nephrology and Renovascular Disease Pub Date : 2021-08-04 eCollection Date: 2021-01-01 DOI:10.2147/IJNRD.S319991

Sisay Deme, Berihu Fisseha, Gebreslassie Kahsay, Haimanot Melese, Abayneh Alamer, Sileshi Ayhualem

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引用次数: 2

Abstract

Background: Musculoskeletal disorders contributed from chronic kidney disease are increasing worldwide. Musculoskeletal disorders had a significant health burden and are leading causes of co-morbidities, disability and low productivity, which potentially affect individual's functional status and quality of life.

Purpose: The aim of this study was to assess the prevalence of musculoskeletal disorders and its associated factors among patients with chronic kidney attending in Saint Paul Hospital, Addis Ababa, Ethiopia.

Patients and methods: An institution-based cross-sectional study was conducted on 302 enrolled study participants through systematic random sampling techniques. Face-to-face interview, physical examination and chart reviews were used to collect data using semi-structured questionnaire adapted from a standard Nordic Musculoskeletal Questionnaire and other literatures. Data were entered into Epi Info version 7 and exported to SPSS version 23 for analysis. Bivariate logistic regression analysis was employed with a p-value less than 0.25. Finally, those variables having a p-value less than 0.05 with 95% CI in multivariate analysis were taken as statistically significant.

Results: The prevalence of musculoskeletal disorders among CKD individuals was found to be 58.6% (95% CI; 53.0, 64.1). Being female (AOR = 0.49; 95% CI 0.26, 0.94), age between 40 and 49 (AOR = 3.34; 95% CI 1.07, 10.44), stage III (AOR = 0.24; 95% CI 0.06, 0.89) and stage IV (AOR = 0.24; 95% CI 0.06, 0.89) chronic kidney disease, having HTN (AOR = 7.47; 95% CI 3.47, 16.06), parathyroid hormone level ≥100 pg/mL (AOR = 0.43; 95% CI 0.21, 0.87), calcium level <8.4 mg/dl (AOR = 5.89; 95% CI 2.66, 13.56) and serum 25 hydroxy vitamin D level <20 ng/mL (AOR = 3.91; 95% CI 1.32, 11.56) were significantly associated with musculoskeletal disorders.

Conclusion: MSDs were shown to be moderately common in CKD patients. Female gender, age between 40 and 49 yrs, stage III and stage IV CKD, hypertension, higher PTH level, lower calcium level and lower vitamin D level were statistically significant in their association with musculoskeletal disorders.

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埃塞俄比亚亚的斯亚贝巴圣保罗医院慢性肾病患者的肌肉骨骼疾病及相关因素

背景:慢性肾脏疾病引起的肌肉骨骼疾病在世界范围内正在增加。肌肉骨骼疾病具有重大的健康负担，是合并症、残疾和低生产力的主要原因，可能影响个人的功能状态和生活质量。目的:本研究的目的是评估在埃塞俄比亚亚的斯亚贝巴圣保罗医院就诊的慢性肾病患者中肌肉骨骼疾病的患病率及其相关因素。患者和方法:采用系统随机抽样技术，对302名入组的研究对象进行了基于机构的横断面研究。采用面对面访谈、体格检查和图表回顾等方法收集数据，采用半结构化问卷，改编自标准北欧肌肉骨骼问卷和其他文献。数据输入Epi Info version 7，导出到SPSS version 23进行分析。采用双变量logistic回归分析，p值小于0.25。最后，将多变量分析中p值小于0.05且95% CI的变量视为具有统计学意义。结果:慢性肾病个体中肌肉骨骼疾病的患病率为58.6% (95% CI;53.0, 64.1)。女性(AOR = 0.49;95% CI 0.26, 0.94)，年龄在40 ~ 49岁之间(AOR = 3.34;95% CI 1.07, 10.44)， III期(AOR = 0.24;95% CI 0.06, 0.89)和IV期(AOR = 0.24;95% CI 0.06, 0.89)慢性肾脏疾病，有HTN (AOR = 7.47;95% CI 3.47, 16.06)，甲状旁腺激素水平≥100 pg/mL (AOR = 0.43;95% CI 0.21, 0.87)，钙水平结论:MSDs在CKD患者中较为常见。女性、年龄在40 ~ 49岁之间、CKD III期和IV期、高血压、PTH水平升高、钙水平降低、维生素D水平降低与肌肉骨骼疾病的相关性有统计学意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Nephrology and Renovascular Disease UROLOGY & NEPHROLOGY-

CiteScore

3.90

自引率

5.00%

发文量

审稿时长

16 weeks

期刊介绍： International Journal of Nephrology and Renovascular Disease is an international, peer-reviewed, open-access journal focusing on the pathophysiology of the kidney and vascular supply. Epidemiology, screening, diagnosis, and treatment interventions are covered as well as basic science, biochemical and immunological studies. In particular, emphasis will be given to: -Chronic kidney disease- Complications of renovascular disease- Imaging techniques- Renal hypertension- Renal cancer- Treatment including pharmacological and transplantation- Dialysis and treatment of complications of dialysis and renal disease- Quality of Life- Patient satisfaction and preference- Health economic evaluations. The journal welcomes submitted papers covering original research, basic science, clinical studies, reviews & evaluations, guidelines, expert opinion and commentary, case reports and extended reports. The main focus of the journal will be to publish research and clinical results in humans but preclinical, animal and in vitro studies will be published where they shed light on disease processes and potential new therapies and interventions.