Impact of SARS-CoV-2 on Ocular Surface Pathology and Treatment Practices: a Review.

IF 0.9 Q4 OPHTHALMOLOGY Current Ophthalmology Reports Pub Date : 2021-01-01 Epub Date: 2021-08-05 DOI:10.1007/s40135-021-00271-3
Sila Bal, James Chodosh, Nandini Venkateswaran
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引用次数: 4

Abstract

Purpose of review: The ocular surface is a potential site of ocular involvement by SARS-CoV-2 infection. We performed a review of the literature to understand the pathogenesis of SARS-CoV-2 disease manifestations on the ocular surface as well as to elucidate emerging treatment patterns and practice changes during the COVID-19 pandemic.

Recent findings: The ocular manifestations of SARS-CoV-2 are likely limited to a mild and transient conjunctivitis. Other manifestations have not been validated in larger cohorts. Ocular surface tissue should be considered potentially infectious due to the presence of host receptors on surface tissues. The availability of donor tissue in lower-middle income countries has been greatly impacted by the pandemic and would benefit from further investigation into transmissibility through donor tissue.

Summary: Transmission of SARS-CoV-2 through the ocular surface has yet to be confirmed. The most common ocular manifestation is a mild conjunctivitis. Ocular surface surgeons face specific challenges in the use of donor tissues and aerosolizing procedures and have adapted practice patterns accordingly.

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SARS-CoV-2对眼表病理及治疗实践的影响
综述目的:眼表是SARS-CoV-2感染可能累及眼部的部位。我们对文献进行了回顾,以了解SARS-CoV-2疾病在眼表表现的发病机制,并阐明COVID-19大流行期间新出现的治疗模式和实践变化。最新发现:SARS-CoV-2的眼部表现可能仅限于轻度和短暂性结膜炎。其他表现尚未在更大的队列中得到验证。由于眼表组织上存在宿主受体,因此应认为眼表组织具有潜在传染性。中低收入国家的供体组织供应受到大流行的极大影响,并将受益于对通过供体组织传播的进一步调查。摘要:SARS-CoV-2通过眼表传播尚未得到证实。最常见的眼部表现是轻度结膜炎。眼表外科医生在使用供体组织和雾化过程中面临着特殊的挑战,并相应地调整了实践模式。
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来源期刊
Current Ophthalmology Reports
Current Ophthalmology Reports Medicine-Ophthalmology
CiteScore
2.00
自引率
0.00%
发文量
22
期刊介绍: This journal aims to offer expert review articles on the most significant recent developments in the field of ophthalmology. By providing clear, insightful, balanced contributions, the journal intends to serve those who diagnose, treat, manage, and prevent ocular conditions and diseases. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas across the field. Section Editors select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An Editorial Board of more than 20 internationally diverse members reviews the annual table of contents, ensures that topics include emerging research, and suggests topics of special importance to their country/region. Topics covered may include age-related macular degeneration; diabetic retinopathy; dry eye syndrome; glaucoma; pediatric ophthalmology; ocular infections; refractive surgery; and stem cell therapy.
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