An Interesting Case of Bilateral Facial Palsy due to Granulomatosis with Polyangiitis.

Case Reports in Rheumatology Pub Date : 2021-08-04 eCollection Date: 2021-01-01 DOI:10.1155/2021/9963564
Rajish Sanjit Kumar Shil, Jamal Ali Teir
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Abstract

Granulomatosis with polyangiitis (formerly called Wegener's granulomatosis) is a systemic autoimmune disease, which can lead to necrotizing vasculitis affecting small vessels and cause inflammation of blood vessels in the nose, sinuses, throat, lungs, and kidneys. In rare instances, it has shown involvement of the brain and cranial nerves as well. We are reporting a case of granulomatosis with polyangiitis, complicated by bilateral facial palsy due to lower motor neuron involvement of the facial nerve, which has responded well to immunosuppressive treatment, particularly rituximab. It is prudent to be vigilant in investigating patients with atypical presentation for systemic autoimmune diseases, as this approach would affect the patient morbidity and mortality with early initiation of treatment for the disease.

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肉芽肿病合并多血管炎致双侧面瘫一例。
肉芽肿伴多血管炎(以前称为韦格纳肉芽肿病)是一种全身性自身免疫性疾病,可导致坏死性血管炎,影响小血管,并引起鼻子、鼻窦、喉咙、肺部和肾脏的血管炎症。在极少数情况下,它也显示出涉及大脑和颅神经。我们报告了一例肉芽肿病伴多血管炎,由于面神经的下运动神经元受累而并发双侧面瘫,该病对免疫抑制治疗,特别是利妥昔单抗反应良好。谨慎的做法是在调查系统性自身免疫性疾病非典型表现的患者时保持警惕,因为这种方法会影响患者的发病率和死亡率,并尽早开始治疗该疾病。
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审稿时长
12 weeks
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