[Urinary bladder microbiome analysis and probiotic treatment options for women with recurrent urinary tract infections].

Der Urologe. Ausg. A Pub Date : 2022-01-01 Epub Date: 2021-08-23 DOI:10.1007/s00120-021-01621-6
T Schiereck, S Yeldan, J Kranz, L Schneidewind, F Wagenlehner, I Wieters, M J G T Vehreschild, T Otto, D Barski
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Abstract

Novel preventive measures and therapeutic approaches are needed to reduce the frequency of recurrent urinary tract infections (rUTI) and the associated emergence of multidrug-resistant uropathogens. The aim of this review is to systematically present the available evidence on the urinary bladder microbiome of healthy women and those with rUTIs. In addition, relevant studies on the efficacy of probiotics in rUTIs are presented in a structured manner. This will provide an overview on the current state of research and an outlook on treatment strategies beyond the usual antimicrobial options.

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[膀胱微生物组分析和针对复发性尿路感染妇女的益生菌治疗方案]。
要降低复发性尿路感染(rUTI)的发生率以及与之相关的耐多药尿路病原体的出现,就需要采取新的预防措施和治疗方法。本综述旨在系统地介绍有关健康女性和复发性尿路感染患者膀胱微生物组的现有证据。此外,还以结构化的方式介绍了益生菌对急性尿路感染疗效的相关研究。这将概述目前的研究状况,并展望除常规抗菌药物之外的治疗策略。
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