The management of asymptomatic carotid stenosis: Is there a benefit to operate elderly patients?

IF 17.7 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2020-10-01 eCollection Date: 2020-09-01 DOI:10.37825/2239-9747.1017

N M Bouayed, A Sekkal

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引用次数: 1

Abstract

Background: We present a retrospective study of a series of 40 patients over the age of 75 operated for an asymptomatic carotid stenosis. The results were evaluated during an average of 3 years of follow-up.

Material and method: The study is retrospective and monocentric. The series includes 40 patients aged over 75 years and with an average age of 78.5 years (range 75-82). Patients underwent surgery for an asymptomatic carotid stenosis of more than 80%. The technique in all case was a carotid endarterectomy.

Results: There have been no postoperative deaths or neurological adverse events. During an average follow-up of 3 years, there was one death secondary to colon cancer. However, 5 patients were lost to follow-up.

Conclusion: Carotid surgery in elderly patients may have a benefit. However, our study has shortcomings. It is retrospective and the patient cohort is reduced. A randomized, prospective study, comparing surgery or angioplasty with the best medical treatment, is necessary to choose the most effective and safest treatment to offer to an elderly patient with asymptomatic carotid stenosis.

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无症状颈动脉狭窄的治疗:老年患者手术是否有好处?

背景：我们对40名75岁以上的无症状颈动脉狭窄患者进行了回顾性研究。在平均3年的随访中对结果进行了评估。材料与方法：本研究为回顾性、单中心研究。该系列包括40名年龄在75岁以上的患者，平均年龄为78.5岁（75-82岁）。患者接受了超过80%的无症状颈动脉狭窄的手术。所有病例的技术都是颈动脉内膜切除术。结果：无术后死亡或神经系统不良事件。在平均3年的随访中，有一例死于癌症。然而，有5名患者在随访中丢失。结论：颈动脉手术治疗老年患者可能有一定的疗效。然而，我们的研究存在不足。它具有回顾性，患者队列减少。有必要对无症状颈动脉狭窄的老年患者进行随机、前瞻性研究，将手术或血管成形术与最佳药物治疗进行比较，以选择最有效、最安全的治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.