New wine in old bottles: 68Ga-PSMA-11 PET/CT reveals COVID-19 in patients with prostate cancer.

IF 2 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING American journal of nuclear medicine and molecular imaging Pub Date : 2021-08-15 eCollection Date: 2021-01-01
Hanyi Fang, Muhsin H Younis, Weibo Cai, Xiaoli Lan, Dawei Jiang
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Abstract

The COVID-19 pandemic continues to influence every aspect of human life across the globe. It was reported that vascular angiogenesis of COVID-19 was elevated in patients with equally severe influenza virus infection. In this issue of AJNMMI, Farolfi et al. reported that there was lung uptake not related to prostate cancer in almost all COVID-19 patients who performed 68Ga-PSMA-11 PET/CT scans and most of the lung uptake lesions were matched with typical CT patterns of COVID-19. With the advantages of having various tracers for whole-body imaging, PET provides opportunities to study the mechanism of COVID-19 from different aspects and obtain patterns of extrapulmonary lesions in COVID-19, which helps explore more effective treatments for the patients. This case series opened the door to many future studies. Furthermore, such a multi-national/multi-institutional collaboration in the pandemic truly encouraged us that science is indeed without borders.

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旧瓶装新酒:68Ga-PSMA-11 PET/CT 揭示前列腺癌患者体内的 COVID-19。
COVID-19 大流行继续影响着全球人类生活的方方面面。据报道,在同样严重的流感病毒感染患者中,COVID-19 的血管生成率升高。在本期的 AJNMMI 杂志上,Farolfi 等人报告说,几乎所有接受 68Ga-PSMA-11 PET/CT 扫描的 COVID-19 患者都存在与前列腺癌无关的肺部摄取,而且大多数肺部摄取病灶与 COVID-19 的典型 CT 模式相匹配。PET具有多种示踪剂全身成像的优势,可以从不同方面研究COVID-19的发病机制,获得COVID-19肺外病变的模式,有助于探索更有效的治疗方法。该系列病例为今后的研究打开了一扇大门。此外,这种多国/多机构在大流行病中的合作确实鼓励了我们,科学确实是无国界的。
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来源期刊
American journal of nuclear medicine and molecular imaging
American journal of nuclear medicine and molecular imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
自引率
4.00%
发文量
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期刊介绍: The scope of AJNMMI encompasses all areas of molecular imaging, including but not limited to: positron emission tomography (PET), single-photon emission computed tomography (SPECT), molecular magnetic resonance imaging, magnetic resonance spectroscopy, optical bioluminescence, optical fluorescence, targeted ultrasound, photoacoustic imaging, etc. AJNMMI welcomes original and review articles on both clinical investigation and preclinical research. Occasionally, special topic issues, short communications, editorials, and invited perspectives will also be published. Manuscripts, including figures and tables, must be original and not under consideration by another journal.
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