Genomics in medicine: A new era in medicine.

Vishwanath Pattan, Rahul Kashyap, Vikas Bansal, Narsimha Candula, Thoyaja Koritala, Salim Surani
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引用次数: 4

Abstract

The sequencing of complete human genome revolutionized the genomic medicine. However, the complex interplay of gene-environment-lifestyle and influence of non-coding genomic regions on human health remain largely unexplored. Genomic medicine has great potential for diagnoses or disease prediction, disease prevention and, targeted treatment. However, many of the promising tools of genomic medicine are still in their infancy and their application may be limited because of the limited knowledge we have that precludes its use in many clinical settings. In this review article, we have reviewed the evolution of genomic methodologies/tools, their limitations, and scope, for current and future clinical application.

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医学中的基因组学:医学的新时代。
人类全基因组测序使基因组医学发生了革命性的变化。然而,基因-环境-生活方式的复杂相互作用以及非编码基因组区域对人类健康的影响在很大程度上仍未被探索。基因组医学在疾病的诊断或预测、疾病的预防和靶向治疗方面具有巨大的潜力。然而,许多有前途的基因组医学工具仍处于起步阶段,它们的应用可能受到限制,因为我们拥有的知识有限,无法在许多临床环境中使用。在这篇综述文章中,我们回顾了基因组方法/工具的发展,它们的局限性,以及当前和未来临床应用的范围。
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