RSV: perspectives to strengthen the need for protection in all infants.

IF 3.6 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Emerging Themes in Epidemiology Pub Date : 2021-10-21 DOI:10.1186/s12982-021-00104-5
Jose Antonio Navarro Alonso, Louis J Bont, Elena Bozzola, Egbert Herting, Federico Lega, Silke Mader, Marta C Nunes, Octavio Ramilo, George Valiotis, Catherine Weil Olivier, Ann Yates, Saul N Faust
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引用次数: 11

Abstract

Respiratory syncytial virus (RSV)-the most common viral cause of bronchiolitis-is a significant cause of serious illness among young children between the ages of 0-5 years and is especially concerning in the first year of life. Globally, RSV is a common cause of childhood acute lower respiratory illness (ALRI) and a major cause of hospital admissions in young children and infants and represents a substantial burden for health-care systems. This burden is strongly felt as there are currently no effective preventative options that are available for all infants. However, a renaissance in RSV prevention strategies is unfolding, with several new prophylactic options such as monoclonal antibodies and maternal vaccinations that are soon to be available. A key concern is that health decision makers and systems may not be ready to take full advantage of forthcoming technological innovations. A multi-stakeholder approach is necessary to bridge data gaps to fully utilise upcoming options. Knowledge must be made available at multiple levels to ensure that parents and doctors are aware of preventative options, but also to ensure that stakeholders and policymakers are given the necessary information to best advise implementation strategies.

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呼吸道合胞病毒:加强所有婴儿保护需求的观点。
呼吸道合胞病毒(RSV)是引起毛细支气管炎最常见的病毒,是0-5岁幼儿严重疾病的重要原因,尤其在生命的第一年引起关注。在全球范围内,呼吸道合胞病毒是儿童急性下呼吸道疾病(ALRI)的常见病因,也是幼儿和婴儿住院的主要原因,是卫生保健系统的重大负担。由于目前没有针对所有婴儿的有效预防选择,因此强烈感受到这种负担。然而,RSV预防策略的复兴正在展开,一些新的预防选择,如单克隆抗体和母亲疫苗接种将很快可用。一个关键的关切是,卫生决策者和系统可能没有准备好充分利用即将到来的技术创新。多方利益攸关方的做法是必要的,以弥合数据差距,充分利用即将推出的备选方案。必须在多个层面提供知识,以确保家长和医生了解预防方案,同时也确保向利益攸关方和决策者提供必要的信息,以便为实施战略提供最佳建议。
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来源期刊
Emerging Themes in Epidemiology
Emerging Themes in Epidemiology Medicine-Epidemiology
CiteScore
4.40
自引率
4.30%
发文量
9
审稿时长
28 weeks
期刊介绍: Emerging Themes in Epidemiology is an open access, peer-reviewed, online journal that aims to promote debate and discussion on practical and theoretical aspects of epidemiology. Combining statistical approaches with an understanding of the biology of disease, epidemiologists seek to elucidate the social, environmental and host factors related to adverse health outcomes. Although research findings from epidemiologic studies abound in traditional public health journals, little publication space is devoted to discussion of the practical and theoretical concepts that underpin them. Because of its immediate impact on public health, an openly accessible forum is needed in the field of epidemiology to foster such discussion.
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