The effect of preexisting medical comorbidities on the preeclamptic phenotype: a retrospective cohort study.

IF 1.5 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Hypertension in Pregnancy Pub Date : 2021-11-01 Epub Date: 2021-10-26 DOI:10.1080/10641955.2021.1991371
Michael S Tanner, Deborah De Guingand, Maya Reddy, Saskia Rowson, Daniel L Rolnik, Fabricio Da Silva Costa, Mary-Ann Davey, Ben W Mol, Euan M Wallace, Kirsten R Palmer
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Abstract

Objective:To compare the effect of comorbidities on the phenotype and outcomes of preeclampsia.Methods: A matched retrospective cohort study of women delivering at a tertiary maternity center following a diagnosis of preeclampsia. We collected data on signs and symptoms, biochemical markers, and maternal and perinatal outcomes.Results:We studied 474 women; 158 women with and 316 without comorbidities. Compared to women without comorbidities, women with comorbidities delivered earlier. They suffered fewer maternal but more neonatal complications.Conclusion: Women with comorbidities receive earlier intervention than women without comorbidities, which may lead to fewer maternal complications but worse neonatal outcomes.

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既往医学合并症对子痫前期表型的影响:一项回顾性队列研究
目的:比较合并症对子痫前期表型和预后的影响。方法:一项匹配的回顾性队列研究的妇女分娩后,诊断先兆子痫在三级妇产中心。我们收集了体征和症状、生化指标以及孕产妇和围产期结局的数据。结果:我们研究了474名女性;158名女性有合并症,316名女性无合并症。与没有合并症的妇女相比,有合并症的妇女分娩更早。她们的产妇并发症较少,但新生儿并发症较多。结论:有合并症的妇女比无合并症的妇女接受更早的干预,这可能导致更少的产妇并发症,但更差的新生儿结局。
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来源期刊
Hypertension in Pregnancy
Hypertension in Pregnancy 医学-妇产科学
CiteScore
3.40
自引率
0.00%
发文量
21
审稿时长
6 months
期刊介绍: Hypertension in Pregnancy is a refereed journal in the English language which publishes data pertaining to human and animal hypertension during gestation. Contributions concerning physiology of circulatory control, pathophysiology, methodology, therapy or any other material relevant to the relationship between elevated blood pressure and pregnancy are acceptable. Published material includes original articles, clinical trials, solicited and unsolicited reviews, editorials, letters, and other material deemed pertinent by the editors.
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