Vitamins are Indeed Vital Amines: A Discussion of 3 Deficiencies With Neurologic Manifestations.

Child neurology open Pub Date : 2021-10-23 eCollection Date: 2021-01-01 DOI:10.1177/2329048X211046440
Bedirhan Tarhan, Sydur Rahman, Nancy Joseph, Douglas Hyder, Carla Zingariello, Peggy R Borum, John Sladky, Steven Parrish Winesett
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Abstract

Optimal functioning of the human nervous system depends on a constant supply of nutrients, vitamins, and minerals. In the developed world, nutritional deficiencies are relatively rare and infrequently present with neurologic manifestations. These neurologic disorders can be mistaken for inflammatory and/or autoimmune phenomena. This manuscript describes 2 pediatric cases with neurologic signs/symptoms arising from vitamin deficiencies-(1) optic neuropathy and (2) Wernicke encephalopathy associated with a Guillain-Barre-like pattern of weakness. The 2 cases and the subsequent discussion of vitamin A, B1, and B12 deficiencies underscore the value of taking a thorough dietary history and emphasize risk factors for these 3 nutritional deficiencies.

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维生素确实是重要的胺:讨论 3 种具有神经系统表现的缺乏症。
人体神经系统的最佳功能取决于营养物质、维生素和矿物质的持续供应。在发达国家,营养缺乏症相对罕见,也很少出现神经系统表现。这些神经系统疾病可能被误认为是炎症和/或自身免疫现象。本手稿描述了 2 例因缺乏维生素而出现神经系统体征/症状的儿科病例--(1) 视神经病变和 (2) Wernicke 脑病伴格林-巴利样乏力。这两个病例以及随后对维生素 A、B1 和 B12 缺乏症的讨论强调了全面了解饮食史的价值,并强调了这三种营养缺乏症的风险因素。
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