Pulmonary metastatic melanoma: current state of diagnostic imaging and treatments.

IF 1 Q4 ONCOLOGY Melanoma Management Pub Date : 2021-07-09 eCollection Date: 2021-09-01 DOI:10.2217/mmt-2021-0001

Kermit S Zhang, Tomer Pelleg, Sabrina Campbell, Catalina Rubio, Anthony Lukas Loschner, Susanti Ie

引用次数: 8

Abstract

Melanoma is the deadliest form of skin cancer with an estimated incidence of over 160,000 cases annually and about 41,000 melanoma-related deaths per year worldwide. Malignant melanoma (MM) primarily occurs in the skin but has been described in other organs. Although the respiratory system is generally afflicted by tumors such as lung cancer, it is also rarely affected by primary MM. The estimated incidence of pulmonary MM of the lung accounts for 0.01% of all primary lung tumors. The current understanding of pulmonary MM of the lung pathophysiology and its management are not well established. We aim to survey current clinical modalities with a focus on diagnostic imaging and therapeutic intervention to guide providers in the management of patients with a high index of suspicion.

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肺转移性黑色素瘤:诊断、影像学和治疗的现状。

黑色素瘤是最致命的一种皮肤癌，估计每年有超过16万例病例，全世界每年约有4.1万例与黑色素瘤相关的死亡。恶性黑色素瘤(MM)主要发生在皮肤，但也有在其他器官的描述。虽然肺癌等肿瘤多累及呼吸系统，但原发性MM也很少累及呼吸系统。据估计，肺MM的发病率仅占所有原发性肺肿瘤的0.01%。目前对肺MM肺病理生理及治疗的认识尚不完善。我们的目标是调查当前的临床模式，重点是诊断成像和治疗干预，以指导提供者管理高怀疑指数的患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Melanoma Management ONCOLOGY-

CiteScore

5.10

自引率

0.00%

发文量

审稿时长

13 weeks

期刊介绍： Skin cancer is on the rise. According to the World Health Organization, 132,000 melanoma skin cancers occur globally each year. While early-stage melanoma is usually relatively easy to treat, once disease spreads prognosis worsens considerably. Therefore, research into combating advanced-stage melanoma is a high priority. New and emerging therapies, such as monoclonal antibodies, B-RAF and KIT inhibitors, antiangiogenic agents and novel chemotherapy approaches hold promise for prolonging survival, but the search for a cure is ongoing. Melanoma Management publishes high-quality peer-reviewed articles on all aspects of melanoma, from prevention to diagnosis and from treatment of early-stage disease to late-stage melanoma and metastasis. The journal presents the latest research findings in melanoma research and treatment, together with authoritative reviews, cutting-edge editorials and perspectives that highlight hot topics and controversy in the field. Independent drug evaluations assess newly approved medications and their role in clinical practice. Key topics covered include: Risk factors, prevention and sun safety education Diagnosis, staging and grading Surgical excision of melanoma lesions Sentinel lymph node biopsy Biological therapies, including immunotherapy and vaccination Novel chemotherapy options Treatment of metastasis Prevention of recurrence Patient care and quality of life.