[Prostate-specific membrane antigen positron emission tomography (PSMA PET) for urologists-when and which tracer?]

Der Urologe. Ausg. A Pub Date : 2022-04-01 Epub Date: 2022-02-09 DOI:10.1007/s00120-022-01766-y
Christoph Berliner, Claudia Kesch, Wolfgang P Fendler, Matthias Eiber, Tobias Maurer
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Abstract

Background: Prostate-specific membrane antigen positron emission tomography (PSMA PET) is increasingly replacing conventional imaging for staging of prostate cancer. A major challenge is its appropriate use and correct interpretation.

Objectives: How and when is PSMA PET used in patient care to optimally direct therapy?

Materials and methods: Systematic presentation and discussion of the current state of knowledge, guidelines and expert knowledge on PSMA PET with a summary of ongoing studies.

Conclusion: PSMA PET is the new standard for systemic staging of prostate cancer, enabling precision patient care with novel local, oligometastatic, and systemic treatment approaches.

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[用于泌尿科医生的前列腺特异性膜抗原正电子发射断层扫描(PSMA PET)何时以及使用哪种示踪剂?]
背景:前列腺特异性膜抗原正电子发射断层扫描(PSMA PET)正在逐渐取代传统的前列腺癌分期成像。一个主要的挑战是它的恰当使用和正确解释。目的:PSMA PET如何以及何时用于患者护理以最佳地指导治疗?材料和方法:系统地介绍和讨论PSMA PET的知识现状、指南和专家知识,并总结正在进行的研究。结论:PSMA PET是前列腺癌系统性分期的新标准,可以通过新颖的局部、少转移和全身治疗方法实现精确的患者护理。
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