The EpiDiverse Plant Epigenome-Wide Association Studies (EWAS) Pipeline.

IF 2.5 Q3 GENETICS & HEREDITY Epigenomes Pub Date : 2021-05-04 DOI:10.3390/epigenomes5020012
Sultan Nilay Can, Adam Nunn, Dario Galanti, David Langenberger, Claude Becker, Katharina Volmer, Katrin Heer, Lars Opgenoorth, Noe Fernandez-Pozo, Stefan A Rensing
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引用次数: 3

Abstract

Bisulfite sequencing is a widely used technique for determining DNA methylation and its relationship with epigenetics, genetics, and environmental parameters. Various techniques were implemented for epigenome-wide association studies (EWAS) to reveal meaningful associations; however, there are only very few plant studies available to date. Here, we developed the EpiDiverse EWAS pipeline and tested it using two plant datasets, from P. abies (Norway spruce) and Q. lobata (valley oak). Hence, we present an EWAS implementation tested for non-model plant species and describe its use.

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EpiDiverse植物表观基因组关联研究(EWAS)管道。
亚硫酸氢盐测序是一种广泛使用的技术,用于确定DNA甲基化及其与表观遗传学、遗传学和环境参数的关系。采用各种技术进行全表观基因组关联研究(EWAS)以揭示有意义的关联;然而,迄今为止只有很少的植物研究。在这里,我们开发了EpiDiverse EWAS管道,并使用两种植物数据集进行了测试,分别是P. abies(挪威云杉)和Q. lobata(山谷橡树)。因此,我们提出了一个EWAS实现测试非模式植物物种和描述其使用。
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来源期刊
Epigenomes
Epigenomes GENETICS & HEREDITY-
CiteScore
3.80
自引率
0.00%
发文量
38
审稿时长
11 weeks
期刊最新文献
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