Intergenerational Costs of Oxidative Stress: Reduced Fitness in Daughters of Mothers That Experienced High Levels of Oxidative Damage during Reproduction.
Ana Ángela Romero-Haro, Lorenzo Pérez-Rodríguez, Barbara Tschirren
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引用次数: 2
Abstract
AbstractParental condition transfer effects occur when the parents' physiological state during reproduction affects offspring performance. Oxidative damage may mediate such effects, yet evidence that oxidative damage experienced by parents during reproduction negatively affects offspring fitness is scarce and limited to early life stages. We show in Japanese quail (Coturnix japonica) that maternal levels of oxidative damage, measured during reproduction, negatively predict the number of offspring produced by daughters. This maternal effect on daughters' reproductive success was mediated by an effect on hatching success rather than on the number of eggs laid by daughters. We also observed a negative association between fathers' oxidative damage levels and the number of eggs laid by daughters but a positive association between fathers' oxidative damage levels and the hatching success of those eggs. These opposing paternal effects canceled each other out, resulting in no overall effect on the number of offspring produced by daughters. No significant association between a female's own level of oxidative damage during reproduction and her reproductive success was observed. Our results suggest that oxidative damage experienced by parents is a better predictor of an individual's reproductive performance than oxidative damage experienced by the individual itself. Although the mechanisms underlying these parental condition transfer effects are currently unknown, changes in egg composition or (epi)genetic alterations of gametes may play a role. These findings highlight the importance of an intergenerational perspective when quantifying costs of physiological stress.
期刊介绍:
Physiological and Biochemical Zoology: Ecological and Evolutionary Approaches primarily publishes original research in animal physiology and biochemistry as considered from behavioral, ecological, and/or evolutionary perspectives. Studies at all levels of biological organization from the molecular to the whole organism are welcome, and work that integrates across levels of organization is particularly encouraged. Studies that focus on behavior or morphology are welcome, so long as they include ties to physiology or biochemistry, in addition to having an ecological or evolutionary context.
Subdisciplines of interest include nutrition and digestion, salt and water balance, epithelial and membrane transport, gas exchange and transport, acid-base balance, temperature adaptation, energetics, structure and function of macromolecules, chemical coordination and signal transduction, nitrogen metabolism and excretion, locomotion and muscle function, biomechanics, circulation, behavioral, comparative and mechanistic endocrinology, sensory physiology, neural coordination, and ecotoxicology ecoimmunology.