Zeinab Mehrabi, Maryam Salimi, Kianoush Niknam, Farzaneh Mohammadi, Hesan Jelodari Mamaghani, Mohammad Reza Sasani, Mohammad Javad Ashraf, Amirhossein Salimi, Mohammad Hassan Zahedroozegar, Zohreh Erfani
{"title":"Sinoorbital Mucormycosis Associated with Corticosteroid Therapy in COVID-19 Infection.","authors":"Zeinab Mehrabi, Maryam Salimi, Kianoush Niknam, Farzaneh Mohammadi, Hesan Jelodari Mamaghani, Mohammad Reza Sasani, Mohammad Javad Ashraf, Amirhossein Salimi, Mohammad Hassan Zahedroozegar, Zohreh Erfani","doi":"10.1155/2021/9745701","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Mucormycosis is a rare and invasive fungal infection, affecting almost exclusively immunocompromised individuals. Immunosuppressive effects of corticosteroids which are widely prescribed in COVID-19 patients might be a predisposing factor for opportunistic infections even though the other factors should also be considered. <i>Case Presentation</i>. A middle-aged man without any significant past medical history was admitted to the hospital due to a severe COVID-19 infection. He received a high dose of corticosteroids as a part of the treatment. Five days after discharge, he presents with a headache and fever. Eventually, orbital mucormycosis was diagnosed for him and he was treated with antifungal medications.</p><p><strong>Conclusion: </strong>Opportunistic infections should be considered during the current pandemic of COVID-19, during which corticosteroids are widely prescribed.</p>","PeriodicalId":0,"journal":{"name":"","volume":" ","pages":"9745701"},"PeriodicalIF":0.0,"publicationDate":"2021-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568553/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2021/9745701","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Mucormycosis is a rare and invasive fungal infection, affecting almost exclusively immunocompromised individuals. Immunosuppressive effects of corticosteroids which are widely prescribed in COVID-19 patients might be a predisposing factor for opportunistic infections even though the other factors should also be considered. Case Presentation. A middle-aged man without any significant past medical history was admitted to the hospital due to a severe COVID-19 infection. He received a high dose of corticosteroids as a part of the treatment. Five days after discharge, he presents with a headache and fever. Eventually, orbital mucormycosis was diagnosed for him and he was treated with antifungal medications.
Conclusion: Opportunistic infections should be considered during the current pandemic of COVID-19, during which corticosteroids are widely prescribed.