[Guideline-based thermal ablation of hepatocellular carcinoma].

4区医学 Q3 Medicine Radiologe Pub Date : 2022-03-01 Epub Date: 2022-01-17 DOI:10.1007/s00117-021-00960-x

Andreas H Mahnken

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引用次数: 2

Abstract

Background: Hepatocellular carcinoma (HCC) is fifth most common cancer worldwide. The German S3 guideline on the diagnosis and the treatment of hepatocellular and biliary carcinoma was recently revised.

Objective: Determination of the current status of thermal ablation in HCC according to the German S3 guideline.

Materials and methods: Based on the current guideline and a selective literature search, the current status on indication and application of thermal ablation in HCC was revisited.

Results: Radiofrequency ablation (RFA) and microwave ablation (MWA) provide similar survival when compared with surgery. Accordingly, RFA und MWA are considered first-line treatments for HCCs ≤ 3 cm in cirrhotic livers. For HCCs with diameters of 3-5 cm, a combination of transarterial chemoembolization and thermal ablation is recommended.

Conclusion: The current S3 guideline on diagnosis and treatment of HCC comprises relevant changes regarding thermal ablation in HCC. The overall role of interventional oncology procedures in the treatment of HCC was reinforced.

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[基于指南的肝细胞癌热消融]。

背景:肝细胞癌(HCC)是全球第五大常见癌症。最近，德国S3指南对肝细胞癌和胆道癌的诊断和治疗进行了修订。目的:根据德国S3指南确定肝细胞癌热消融的现状。材料与方法:在现有指南和选择性文献检索的基础上，回顾热消融治疗HCC的适应症和应用现状。结果:与手术相比，射频消融(RFA)和微波消融(MWA)提供相似的生存期。因此，RFA和MWA被认为是肝硬化hcc≤ 3 cm的一线治疗方法。对于直径为3-5 cm的hcc，建议采用经动脉化疗栓塞和热消融联合治疗。结论:现行的S3 HCC诊疗指南对热消融在HCC中的应用进行了相关修改。介入肿瘤学在HCC治疗中的整体作用得到加强。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Radiologe 医学-核医学

CiteScore

1.10

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Der Radiologe is an internationally recognized journal dealing with all aspects of radiology and serving the continuing medical education of radiologists in clinical and practical environments. The focus is on x-ray diagnostics, angiography computer tomography, interventional radiology, magnet resonance tomography, digital picture processing, radio oncology and nuclear medicine. Comprehensive reviews on a specific topical issue focus on providing evidenced based information on diagnostics and therapy. Freely submitted original papers allow the presentation of important clinical studies and serve the scientific exchange. Review articles under the rubric ''Continuing Medical Education'' present verified results of scientific research and their integration into daily practice.