{"title":"Commentary on Some Recent Theses Relevant to Combating Aging: December 2021.","authors":"Benjamin Zealley","doi":"10.1089/rej.2021.0079","DOIUrl":null,"url":null,"abstract":"<p><p>Theses reviewed in this issue include \"A Rapid Lipid-Based Approach for Normalization of Quantum Dot-Detected Biomarker Expression on Extracellular Vesicles in Complex Biological Samples,\" \"Cancer Dynamics Under a Chemotherapeutic Stress Gradient Using a Microfluidic <i>In Vitro</i> Tumor Environment,\" \"Cells Exhibiting Strong P16ink4a Promoter Activation <i>In Vivo</i> Display Features of Senescence,\" \"HLA-G Dimer Prolongs Kidney Allograft Survival by Inhibiting CD8<sup>+</sup> T Cell Activation and Granzyme B Expression,\" \"Lysophosphatidic Acid Suppression of CD8 T Cell Signaling and Function,\" and \"Targeting Therapeutic T Cells to the Bone Marrow Niche.\"</p>","PeriodicalId":20979,"journal":{"name":"Rejuvenation research","volume":"24 6","pages":"464-469"},"PeriodicalIF":2.2000,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rejuvenation research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1089/rej.2021.0079","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"GERIATRICS & GERONTOLOGY","Score":null,"Total":0}
引用次数: 1
Abstract
Theses reviewed in this issue include "A Rapid Lipid-Based Approach for Normalization of Quantum Dot-Detected Biomarker Expression on Extracellular Vesicles in Complex Biological Samples," "Cancer Dynamics Under a Chemotherapeutic Stress Gradient Using a Microfluidic In Vitro Tumor Environment," "Cells Exhibiting Strong P16ink4a Promoter Activation In Vivo Display Features of Senescence," "HLA-G Dimer Prolongs Kidney Allograft Survival by Inhibiting CD8+ T Cell Activation and Granzyme B Expression," "Lysophosphatidic Acid Suppression of CD8 T Cell Signaling and Function," and "Targeting Therapeutic T Cells to the Bone Marrow Niche."
期刊介绍：
Rejuvenation Research publishes cutting-edge, peer-reviewed research on rejuvenation therapies in the laboratory and the clinic. The Journal focuses on key explorations and advances that may ultimately contribute to slowing or reversing the aging process, and covers topics such as cardiovascular aging, DNA damage and repair, cloning, and cell immortalization and senescence.
Rejuvenation Research coverage includes:
Cell immortalization and senescence
Pluripotent stem cells
DNA damage/repair
Gene targeting, gene therapy, and genomics
Growth factors and nutrient supply/sensing
Immunosenescence
Comparative biology of aging
Tissue engineering
Late-life pathologies (cardiovascular, neurodegenerative and others)
Public policy and social context.
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