Chokeberry juice supplementation in type 2 diabetic patients - impact on health status.

IF 2 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Journal of applied biomedicine Pub Date : 2019-12-01 Epub Date: 2019-11-13 DOI:10.32725/jab.2019.020
Milica Milutinovic, Radmila Velickovic Radovanovic, Katarina Savikin, Sasa Radenkovic, Marjan Arvandi, Milica Pesic, Milica Kostic, Bojana Miladinovic, Suzana Brankovic, Dusanka Kitic
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引用次数: 11

Abstract

Recent literature evidence indicates the potential use of chokeberry preparations in the prevention and treatment of some chronic noncommunicable diseases. The aim of the present study was to evaluate the effects of the three months oral chokeberry juice supplementation in type 2 diabetic patients, as well as its influence on hematological parameters and certain parameters of the renal dysfunction. The study was designed as an open-label trial, which included 35 patients who have received the herbal supplement, polyphenol-rich chokeberry juice (150 ml/day, three times a day for 50 ml), in addition to their standard therapy. Chokeberry juice as a rich source of polyphenol compounds could be an effective preventive and therapeutic agent in diabetes mellitus type 2. Hematological and biochemical parameters were measured at baseline, after 3 months with the chokeberry juice supplementation and after the next 3 months without the chokeberry juice supplementation (follow-up period). Significant difference was noticed in the levels of LDL-cholesterol, glycated hemoglobin and serum creatinine (p < 0.05), as well as in the levels of some hematological parameters, such as white blood cell and lymphocyte count (p < 0.01), hematocrit, blood hemoglobin, mean corpuscular volume, hemoglobin and hemoglobin concentration and red blood cell count (p < 0.05). The daily consumption of the chokeberry juice could improve the health status in patients with type 2 diabetes mellitus, in combination with their standard therapy.

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2型糖尿病患者补充蔓越莓汁对健康状况的影响
最近的文献证据表明,在预防和治疗一些慢性非传染性疾病中,蔓越莓制剂具有潜在的用途。本研究的目的是评估3个月口服枸杞汁对2型糖尿病患者的影响,以及其对血液学参数和肾功能障碍某些参数的影响。该研究被设计为一项开放标签试验,其中包括35名患者,他们接受了草药补充剂,富含多酚的蔓越莓汁(150毫升/天,每天三次,每次50毫升),除了他们的标准治疗。蔓越莓汁富含多酚类化合物,可作为预防和治疗2型糖尿病的有效药物。血液学和生化指标分别在基线、补充了蔓越莓汁3个月后和不补充蔓越莓汁3个月后(随访期)进行测量。两组间ldl -胆固醇、糖化血红蛋白、血清肌酐水平差异有统计学意义(p < 0.05),白细胞、淋巴细胞计数、红细胞压积、血红蛋白、平均红细胞体积、血红蛋白、血红蛋白浓度、红细胞计数等血液学指标差异有统计学意义(p < 0.05)。2型糖尿病患者每日饮用蔓越莓汁,配合其标准治疗,可改善其健康状况。
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来源期刊
Journal of applied biomedicine
Journal of applied biomedicine PHARMACOLOGY & PHARMACY-
CiteScore
2.40
自引率
7.70%
发文量
13
审稿时长
>12 weeks
期刊介绍: Journal of Applied Biomedicine promotes translation of basic biomedical research into clinical investigation, conversion of clinical evidence into practice in all medical fields, and publication of new ideas for conquering human health problems across disciplines. Providing a unique perspective, this international journal publishes peer-reviewed original papers and reviews offering a sensible transfer of basic research to applied clinical medicine. Journal of Applied Biomedicine covers the latest developments in various fields of biomedicine with special attention to cardiology and cardiovascular diseases, genetics, immunology, environmental health, toxicology, neurology and oncology as well as multidisciplinary studies. The views of experts on current advances in nanotechnology and molecular/cell biology will be also considered for publication as long as they have a direct clinical impact on human health. The journal does not accept basic science research or research without significant clinical implications. Manuscripts with innovative ideas and approaches that bridge different fields and show clear perspectives for clinical applications are considered with top priority.
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