Effects of Local Anesthetics With Vasoconstrictors on Dental Pulp Blood Flow and Oxygen Tension.

Q3 Medicine Anesthesia progress Pub Date : 2021-12-01 DOI:10.2344/anpr-68-02-09

Keikoku Tachibana, Masataka Kasahara, Nobuyuki Matsuura, Tatsuya Ichinohe

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引用次数: 1

Abstract

Objective: The aim of this study was to investigate the changes in pulpal blood flow (PBF) and pulpal oxygen tension (PpulpO2) after injecting local anesthetics with vasoconstrictors.

Methods: Under general anesthesia, male Japanese White rabbits were injected with 0.6 mL of 2% lidocaine with 1:80,000 epinephrine (LE) or 3% propitocaine (prilocaine) with 0.03 IU felypressin (PF) at the apical area of the lower incisor.

Results: Relative to baseline, PBF and PpulpO2 significantly decreased 5 minutes after LE or PF injection as compared with saline. The decrease in PBF was significantly lower in the LE group than in the PF group. Although the LE group had a larger decrease in PpulpO2 relative to baseline than the PF group did, that difference was not significant. PBF and PpulpO2 recovered to baseline faster in the PF group than in the LE group.

Conclusion: The injection of local anesthetic solutions containing vasoconstrictors (LE or PF) transiently caused significant decreases in PBF that resulted in significant decreases in PpulpO2. The recovery of PpulpO2 was faster than PBF regardless of the vasoconstrictor used.

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血管收缩剂局部麻醉剂对牙髓血流和氧张力的影响。

目的:观察局部麻醉药加血管收缩剂后牙髓血流量(PBF)和牙髓氧张力(pulpo2)的变化。方法:在全身麻醉下，雄性日本大白兔下门牙尖区注射2%利多卡因加1:8万肾上腺素(LE) 0.6 mL或3%丙比卡因加0.03 IU felypressin (PF)。结果:与生理盐水相比，LE或PF注射后5分钟PBF和PpulpO2明显降低。LE组PBF的下降明显低于PF组。虽然与PF组相比，LE组的PpulpO2相对于基线有更大的下降，但这种差异并不显著。PF组PBF和PpulpO2恢复到基线的速度快于LE组。结论:局部麻醉溶液中含有血管收缩剂(LE或PF)可引起PBF的短暂性显著降低，从而导致PpulpO2的显著降低。无论使用何种血管收缩剂，PpulpO2的恢复速度都快于PBF。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Anesthesia progress Medicine-Medicine (all)

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： Anesthesia Progress is a peer-reviewed journal and the official publication of the American Dental Society of Anesthesiology. The journal is dedicated to providing a better understanding of the advances being made in the art and science of pain and anxiety control in dentistry.

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