The Guiding Significance of Fractional Flow Reserve (FFR) for Coronary Heart Disease Revascularization.
IF 2 4区 医学Q3 MEDICINE, RESEARCH & EXPERIMENTALDiscovery medicinePub Date : 2021-01-01
Maodong Yang, Li Zhang, Han Tang, Dechang Zheng, Jian Wu
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引用次数: 0
Abstract
Coronary angiography is an important diagnostic tool for coronary heart disease. While it can identify anatomical coronary stenosis, its ability to identify hemodynamic changes is limited. The Fractional Flow Reserve (FFR) technique, combined with coronary angiography, facilitates both the functional and anatomical assessment of heart disease. New studies have shown that FFR has unique advantages in guiding percutaneous coronary intervention (PCI), and it is currently being used in coronary artery bypass graft (CABG) as well as for assessing the prognosis of patients after surgery. It may also play a significant role in assessing the patency of a graft. However, some studies have shown that in considering the cardioprotective benefits of CABG, applying FFR guidelines to CABG may reduce or impair its "surgical collateralization" effect and increase the rate of incomplete revascularization. We compared the advantages and disadvantages of FFR to guide PCI and CABG, which will provide health practitioners with useful resources to determine the best diagnosis and treatment for patients.
期刊介绍：
Discovery Medicine publishes novel, provocative ideas and research findings that challenge conventional notions about disease mechanisms, diagnosis, treatment, or any of the life sciences subjects. It publishes cutting-edge, reliable, and authoritative information in all branches of life sciences but primarily in the following areas: Novel therapies and diagnostics (approved or experimental); innovative ideas, research technologies, and translational research that will give rise to the next generation of new drugs and therapies; breakthrough understanding of mechanism of disease, biology, and physiology; and commercialization of biomedical discoveries pertaining to the development of new drugs, therapies, medical devices, and research technology.
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