Micro-computed tomographic evaluation of the effect of fluoride agents on white spot lesions: An in vitro study.

IF 2.6 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Korean Journal of Orthodontics Pub Date : 2022-01-25 DOI:10.4041/kjod.2022.52.1.75

Sook-Chan Hong, Dong-Yul Lee, Yae-Jin Kim

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引用次数: 1

Abstract

Objective: To investigate remineralizing effect of three fluoride regimens on artificially demineralized enamel around orthodontic bracket by analyzing mineral density (MD) acquired from micro-computed tomography (micro-CT).

Methods: Forty-eight bracket bonded bovine incisors were prepared to create demineralized enamel (DE) surface. The samples were divided into four groups according to the fluoride regimen: 1) no fluoridation, 2) 1.23% acidulated phosphate fluoride (APF) gel, 3) fluoridated toothpaste, and 4) 0.05% sodium fluoride mouthwash. Micro-CT was scanned after demineralization (T0), and 2 weeks (T1) and 4 weeks (T2) of fluoridation.

Results: APF gel showed highest remineralization of DE during T1-T0 interval among the groups (p < 0.05); followed by toothpaste, mouthwash and no fluoridation. APF gel and toothpaste demonstrated significant increase in MD after 4 weeks of application (p < 0.05).

Conclusions: Remineralization effects of three fluoride regimens were depicted through micro-CT analysis, of which APF gel was most effective.

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微计算机层析评价氟化物剂对白斑病变的影响:体外研究。

目的:通过显微ct (micro- computer tomography, micro-CT)的矿物质密度(MD)分析，探讨三种氟化方案对正畸托槽周围人工脱矿牙釉质的再矿化效果。方法:制备48个托槽粘接的牛切牙，形成脱矿牙釉质表面。按氟化方案分为4组:1)不加氟，2)1.23%酸化磷酸氟(APF)凝胶，3)加氟牙膏，4)0.05%氟化钠漱口水。脱矿(T0)、氟化2周(T1)和4周(T2)后进行Micro-CT扫描。结果:APF凝胶在t1 ~ t0间期DE再矿化程度最高(p < 0.05);其次是牙膏、漱口水和不加氟。应用4周后，APF凝胶和牙膏的MD均显著升高(p < 0.05)。结论:微ct分析了3种氟化方案的再矿化效果，其中APF凝胶的再矿化效果最好。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Korean Journal of Orthodontics DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.50

自引率

10.50%

发文量

审稿时长

>12 weeks

期刊介绍： The Korean Journal of Orthodontics (KJO) is an international, open access, peer reviewed journal published in January, March, May, July, September, and November each year. It was first launched in 1970 and, as the official scientific publication of Korean Association of Orthodontists, KJO aims to publish high quality clinical and scientific original research papers in all areas related to orthodontics and dentofacial orthopedics. Specifically, its interest focuses on evidence-based investigations of contemporary diagnostic procedures and treatment techniques, expanding to significant clinical reports of diverse treatment approaches. The scope of KJO covers all areas of orthodontics and dentofacial orthopedics including successful diagnostic procedures and treatment planning, growth and development of the face and its clinical implications, appliance designs, biomechanics, TMJ disorders and adult treatment. Specifically, its latest interest focuses on skeletal anchorage devices, orthodontic appliance and biomaterials, 3 dimensional imaging techniques utilized for dentofacial diagnosis and treatment planning, and orthognathic surgery to correct skeletal disharmony in association of orthodontic treatment.