{"title":"Genetics of Dental Caries: Controlled Animal Models.","authors":"Alexandre Rezende Vieira","doi":"10.1159/000520767","DOIUrl":null,"url":null,"abstract":"<p><p>Research in animal models, particularly rodents, has been used as a tool for gaining insight into the genetics contribution to dental caries. This chapter dissects some of these data, particularly the early studies motivated by observations in humans, complementing them with more recent ones designed specifically to map genes for dental caries. Finally, it offers a critical view of the rationale and lack of ethical principles of the use of nonhuman species in research.</p>","PeriodicalId":35771,"journal":{"name":"Monographs in Oral Science","volume":"30 ","pages":"45-60"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Monographs in Oral Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000520767","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/1/25 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"Dentistry","Score":null,"Total":0}
引用次数: 1
Abstract
Research in animal models, particularly rodents, has been used as a tool for gaining insight into the genetics contribution to dental caries. This chapter dissects some of these data, particularly the early studies motivated by observations in humans, complementing them with more recent ones designed specifically to map genes for dental caries. Finally, it offers a critical view of the rationale and lack of ethical principles of the use of nonhuman species in research.
期刊介绍：
For two decades, ‘Monographs in Oral Science’ has provided a source of in-depth discussion of selected topics in the sciences related to stomatology. Senior investigators are invited to present expanded contributions in their fields of special expertise. The topics chosen are those which have generated a long-standing interest, and on which new conceptual insights or innovative biotechnology are making considerable impact. Authors are selected on the basis of having made lasting contributions to their chosen field and their willingness to share their findings with others.
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