{"title":"Heritability of Dental Caries: Twin Studies.","authors":"Alexandre Rezende Vieira","doi":"10.1159/000520768","DOIUrl":null,"url":null,"abstract":"<p><p>The study of twins is a powerful tool to infer the presence and amount of contribution of genetic variation to a particular trait or disease. The ability to compare identical or monozygotic twins with dizygotic twins permits the direct comparison of pairs of individuals that share 100% of their genomic DNA with pairs that share only 50%, with the assumption that these pairs are under the same environment. In the case of dental caries, the environment is same parents, under the same roof, with the same diet, oral hygiene habits, culture, and lifestyle. These data have consistently suggested that a relevant proportion of the variation of dental caries in populations is due to genetics.</p>","PeriodicalId":35771,"journal":{"name":"Monographs in Oral Science","volume":"30 ","pages":"61-70"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Monographs in Oral Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000520768","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/1/25 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"Dentistry","Score":null,"Total":0}
引用次数: 2
Abstract
The study of twins is a powerful tool to infer the presence and amount of contribution of genetic variation to a particular trait or disease. The ability to compare identical or monozygotic twins with dizygotic twins permits the direct comparison of pairs of individuals that share 100% of their genomic DNA with pairs that share only 50%, with the assumption that these pairs are under the same environment. In the case of dental caries, the environment is same parents, under the same roof, with the same diet, oral hygiene habits, culture, and lifestyle. These data have consistently suggested that a relevant proportion of the variation of dental caries in populations is due to genetics.
期刊介绍：
For two decades, ‘Monographs in Oral Science’ has provided a source of in-depth discussion of selected topics in the sciences related to stomatology. Senior investigators are invited to present expanded contributions in their fields of special expertise. The topics chosen are those which have generated a long-standing interest, and on which new conceptual insights or innovative biotechnology are making considerable impact. Authors are selected on the basis of having made lasting contributions to their chosen field and their willingness to share their findings with others.
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