Cutaneous Conundrums in Cardiac Sarcoidosis: A Series on Skin Disease in Immunosuppression.

Q3 Medicine Journal of atrial fibrillation Pub Date : 2020-08-31 eCollection Date: 2020-08-01 DOI:10.4022/jafib.2247
Daisy Young, Sri Harsha Kanuri, Krishna Akella, Ghulam Murtaza, Rakesh Gopinathannair, Dhanunjaya Lakkireddy
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Abstract

Sarcoidosis is a complex systemic condition resulting in formation of non-caseating granulomas. Infiltrative disease in cardiac sarcoidosis can have significant ramifications on mortality and is one of the few indications for systemic immunosuppressive therapy. In the patient on immunosuppressive medication, resultant sequelae such as skin and soft tissue infections are common and must be differentiated from cutaneous forms of sarcoidosis and other skin pathologies. Patients with humoral or cellular immunodeficiencies may have cutaneous lesions secondary to endemic fungi, mycobacterium, viral diseases, parasites, or encapsulated organisms. We report a rare case of cardiac sarcoidosis on immunosuppressive therapy, with a series of cutaneous sequelae due to opportunistic infection.

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心脏结节病的皮肤难题:免疫抑制皮肤病的一系列研究。
结节病是一种复杂的全身性疾病,导致非干酪样肉芽肿的形成。心脏结节病的浸润性疾病可对死亡率产生重大影响,是需要全身免疫抑制治疗的少数适应症之一。在使用免疫抑制药物的患者中,皮肤和软组织感染等后遗症是常见的,必须与皮肤形式的结节病和其他皮肤病变区分开来。体液或细胞免疫缺陷的患者可能有继发于地方性真菌、分枝杆菌、病毒性疾病、寄生虫或包膜生物的皮肤病变。我们报告一例罕见的心脏结节病在免疫抑制治疗,一系列的皮肤后遗症,由于机会性感染。
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来源期刊
Journal of atrial fibrillation
Journal of atrial fibrillation Medicine-Cardiology and Cardiovascular Medicine
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