Effect of prior beta-blocker use on in-hospital atrial fibrillation development in patients with ST-elevation myocardial infarction.

IF 1.5 4区医学 Q3 PERIPHERAL VASCULAR DISEASE Clinical and Experimental Hypertension Pub Date : 2022-04-03 Epub Date: 2022-01-30 DOI:10.1080/10641963.2022.2029473

Fatih Kahraman, Akif Arslan, Abdullah Dogan, Yasin Turker, Serdar Guler

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Abstract

Background and aim: There are conflicting results about the early administration of beta-blockers (bb) on in-hospital mortality and arrhythmias. Here, we wanted to investigate the effects of chronic bb use on in-hospital Atrial Fibrillation (AF) development in ST-Elevation Myocardial Infarction (STEMI) patients.

Materials and methods: A total of 814 consecutive patients with STEMI were included in the study. They were divided into two groups according to whether they are using bb on admission or not. They were followed for AF development in-hospital and predictors of AF were determined by multivariable logistic regression analysis.

Results: Of the 814 patients, 103 (12.67%) patients were already using bb, while 711 (87.3%) were not. There were no significant differences in the frequency of AF development [3 (%2.9) vs 30 (%4.2), p = .788] between the groups. Multivariable logistic regression analysis showed that left atrial (LA) diameter is the only independent predictor of in-hospital AF development.

Conclusions: Our study showed that chronic bb use does not have an effect on in-hospital AF development in STEMI patients. Nevertheless, LA diameter was found to be an independent predictor of AF.

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既往使用受体阻滞剂对st段抬高型心肌梗死患者住院房颤发展的影响

背景和目的:关于早期使用β受体阻滞剂(bb)对住院死亡率和心律失常的影响，有相互矛盾的结果。在这里，我们想研究慢性bb使用对st段抬高型心肌梗死(STEMI)患者住院房颤(AF)发展的影响。材料和方法:共纳入814例连续STEMI患者。根据入院时是否使用bb，他们被分为两组。随访患者的房颤发展情况，并通过多变量logistic回归分析确定房颤的预测因素。结果:814例患者中，103例(12.67%)患者已使用bb, 711例(87.3%)患者未使用bb。两组间房颤发生频率无显著差异[3 (%2.9)vs 30 (%4.2)， p = .788]。多变量logistic回归分析显示左心房内径是院内房颤发生的唯一独立预测因子。结论:我们的研究表明，慢性bb使用对STEMI患者的住院房颤发展没有影响。然而，发现左室直径是房颤的独立预测因子。

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来源期刊

Clinical and Experimental Hypertension 医学-外周血管病

CiteScore

3.90

自引率

0.80%

发文量

审稿时长

6-12 weeks

期刊介绍： Clinical and Experimental Hypertension is a reputable journal that has converted to a full Open Access format starting from Volume 45 in 2023. While previous volumes are still accessible through a Pay to Read model, the journal now provides free and open access to its content. It serves as an international platform for the exchange of up-to-date scientific and clinical information concerning both human and animal hypertension. The journal publishes a wide range of articles, including full research papers, solicited and unsolicited reviews, and commentaries. Through these publications, the journal aims to enhance current understanding and support the timely detection, management, control, and prevention of hypertension-related conditions. One notable aspect of Clinical and Experimental Hypertension is its coverage of special issues that focus on the proceedings of symposia dedicated to hypertension research. This feature allows researchers and clinicians to delve deeper into the latest advancements in this field. The journal is abstracted and indexed in several renowned databases, including Pharmacoeconomics and Outcomes News (Online), Reactions Weekly (Online), CABI, EBSCOhost, Elsevier BV, International Atomic Energy Agency, and the National Library of Medicine, among others. These affiliations ensure that the journal's content receives broad visibility and facilitates its discoverability by professionals and researchers in related disciplines.