Intralesional cryotherapy with triamcinolone and onabotulinumtoxinA injections for umbilical keloid: A case report.

Scars, burns & healing Pub Date : 2021-12-21 eCollection Date: 2021-01-01 DOI:10.1177/20595131211049040
Jennifer Vh Tran, Shantel Dj Lultschik, Sheetal Sapra, Kevin Dong, Klaudija Gusic, Matthew Goldstein
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引用次数: 1

Abstract

Introduction: Keloid scars are therapeutically challenging and although many treatment options exist, there are no specific guidelines, and few reports have discussed keloids in the umbilical region.

Methods: Here, we present a successful treatment of a 31-year-old female with a history of a recurrent keloid in the umbilical region. The keloid was treated using intralesional cryotherapy followed by intralesional onabotulinumtoxinA and triamcinolone acetonide injections.

Discussion: The patient expressed high satisfaction, minimal side effects, and no recurrence.

Conclusion: Overall, due to the low rate of side effects, high patient satisfaction, and absence of recurrence, this treatment modality should be considered as an option for umbilical keloids.

Lay summary: Background to subject: Keloids are a type of scar that are difficult to treat. There are many treatment options available, but there is no single best treatment for keloids that form around the belly button region. Question being asked: Is intralesional cryotherapy with intralesional onabotulinumtoxinA and triamcinolone acetonide injections effective at treating keloids in the belly button region? How the work was conducted: We treated a 31-year-old female with a keloid around the belly button region that returned after prior treatment. The keloid was treated using combination therapy of freezing the keloid from the inside out, which is called intralesional cryotherapy. This was followed by two types of injections, called onabotulinumtoxinA and triamcinolone acetonide, directly into the keloid. What we learned: Overall, due to the low rate of side effects, high patient satisfaction and the keloid not returning, this treatment plan should be considered as an option for keloids in the belly button region. What we did not learn: This treatment may or may not be effective and safe for all patients of all skin types and demographics as this treatment was performed for only one patient.

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曲安奈德和肉毒杆菌毒素注射局部冷冻治疗脐瘢痕疙瘩1例。
瘢痕疙瘩在治疗上具有挑战性,尽管存在许多治疗选择,但没有具体的指导方针,并且很少有报道讨论脐部的瘢痕疙瘩。方法:在这里,我们提出了一个成功的治疗31岁的女性与一个复发性瘢痕疙瘩在脐部的历史。瘢痕疙瘩采用局部冷冻治疗,然后局部注射肉毒杆菌毒素和曲安奈德。讨论:患者满意度高,副作用小,无复发。结论:总的来说,由于副反应率低,患者满意度高,无复发,这种治疗方式应被考虑作为脐带瘢痕疙瘩的一种选择。摘要:主题背景:瘢痕疙瘩是一种难以治疗的疤痕。有很多治疗方法可供选择,但是对于在肚脐周围形成的瘢痕疙瘩,没有一种最好的治疗方法。问题:局部冷冻治疗与局部注射肉毒杆菌毒素和曲安奈德对治疗肚脐区域的瘢痕疙瘩有效吗?工作如何进行:我们治疗了一位31岁的女性,她的肚脐周围有瘢痕疙瘩,在先前的治疗后复发。瘢痕疙瘩的治疗采用从内到外冷冻瘢痕疙瘩的联合疗法,称为病灶内冷冻疗法。接下来是两种类型的注射,分别是肉毒杆菌毒素和曲安奈德,直接注射到瘢痕疙瘩中。研究结果:总的来说,由于副作用发生率低,患者满意度高,瘢痕疙瘩不复发,该治疗方案应被视为治疗肚脐区域瘢痕疙瘩的一种选择。我们没有了解到的是:这种治疗可能对所有皮肤类型和人口统计学的所有患者都有效和安全,也可能不是,因为这种治疗只对一名患者进行了治疗。
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