Gradient boosting for linear mixed models.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2021-01-13 DOI:10.1515/ijb-2020-0136
Colin Griesbach, Benjamin Säfken, Elisabeth Waldmann
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引用次数: 8

Abstract

Gradient boosting from the field of statistical learning is widely known as a powerful framework for estimation and selection of predictor effects in various regression models by adapting concepts from classification theory. Current boosting approaches also offer methods accounting for random effects and thus enable prediction of mixed models for longitudinal and clustered data. However, these approaches include several flaws resulting in unbalanced effect selection with falsely induced shrinkage and a low convergence rate on the one hand and biased estimates of the random effects on the other hand. We therefore propose a new boosting algorithm which explicitly accounts for the random structure by excluding it from the selection procedure, properly correcting the random effects estimates and in addition providing likelihood-based estimation of the random effects variance structure. The new algorithm offers an organic and unbiased fitting approach, which is shown via simulations and data examples.

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线性混合模型的梯度增强。
来自统计学习领域的梯度增强被广泛认为是一个强大的框架,通过适应分类理论的概念,在各种回归模型中估计和选择预测器效应。目前的增强方法还提供了考虑随机效应的方法,从而能够预测纵向和聚类数据的混合模型。然而,这些方法存在一些缺陷,一方面导致不平衡的效应选择,错误地诱导收缩和低收敛率,另一方面导致对随机效应的估计有偏差。因此,我们提出了一种新的增强算法,该算法通过将随机结构排除在选择过程之外,适当地纠正随机效应估计,并提供基于似然的随机效应方差结构估计,从而明确地解释了随机结构。该算法提供了一种有机的、无偏的拟合方法,并通过仿真和数据实例进行了验证。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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