Tayfun Birtay, Suzan Bahadir, Ebru Kabacaoglu, Ozgur Yetiz, Mehmet Fatih Demirci, Gultekin Genctoy
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引用次数: 2
Abstract
Background: SARS-CoV2/COVID-19 emerged in China and caused a global pandemic in 2020. The mortality rate has been reported to be between 0% and 14.6% in all patients. In this study, we determined the clinical and laboratory parameters of COVID-19 related morbidity and mortality in our hospital.
Objectives: Investigate the relationship between demographic, clinical, and laboratory parameters on COVID-19-related morbidity and mortality.
Design: Retrospective observational study.
Settings: Tertiary care hospital.
Patients and methods: Patients diagnosed with COVID-19 pneumonia from March until the end of December were included in the study.
Main outcome measures: The relationship between demographic, clinical, and laboratory parameters and the morbidity and mortality rates of patients diagnosed with COVID-19.
Sample size: 124 patients RESULTS: The mortality rate was 9.6% (12/124). Coronary artery disease (P<.0001) diabetes mellitus (P=.04) fever (>38.3°C) at presentation (P=.04) hypertension (P<.0001), and positive smoking history (P<.0001) were significantly associated with mortality. Patients who died were older, had a higher comorbid disease index, pneumonia severity index, fasting blood glucose, baseline serum creatinine, D-dimer, and had lower baseline haemoglobin, SaO2, percentage of lymphocyte counts and diastolic blood pressure. Patients admitted to the ICU were older, had a higher comorbidity disease index, pneumonia severity index, C-reactive protein, WBC, D-dimer, creatinine, number of antibiotics used, longer O2 support duration, lower hemoglobin, lymphocyte (%), and baseline SaO2 (%).
Conclusions: Our results were consistent with much of the reported data. We suggest that the frequency, dosage, and duration of steroid treatment should be limited.
Limitations: Low patient number, uncertain reason of mortality, no standard treatment regimen, limited treatment options, like ECMO.
期刊介绍：
The Annals of Saudi Medicine (ASM) is published bimonthly by King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. We publish scientific reports of clinical interest in English. All submissions are subject to peer review by the editorial board and by reviewers in appropriate specialties. The journal will consider for publication manuscripts from any part of the world, but particularly reports that would be of interest to readers in the Middle East or other parts of Asia and Africa. Please go to the Author Resource Center for additional information.
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