Administration of the fixed combination of latanoprost 0.005% and timolol 0.5% in glaucoma patients with an intraocular pressure over 30 mmHg.

Clinical ophthalmology (Auckland, N.Z.) Pub Date : 2009-01-01 Epub Date: 2009-06-02 DOI:10.2147/opth.s5128

Yelda Buyru Ozkurt, Tomris Sengor, Tufan Evciman, Melih Haboğlu, Gökçen Baş, Sevda Aydin

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引用次数: 3

Abstract

Purpose: To evaluate the intraocular pressure (IOP) reducing effect of a fixed combination of 0.005% latanoprost and 0.5% timolol in patients with an IOP of 30 mmHg or higher.

Design: Prospective, randomized clinical trial.

Participants: Twenty-eight patients.

Methods: Patients had received no prior medical glaucoma treatment. Routine ophthalmic examinations and visual field tests were performed before and after treatment for each patient.

Results: Mean IOP was 32.28 +/- 0.92 mmHg before treatment. Mean IOP levels were 18.75 +/- 0.68 for the first day, 17.96 +/- 0.90 for the first week and 17.64 +/- 0.66 for the first month after treatment.

Conclusion: A fixed combination of latanoprost 0.005% and timolol 0.5% is effective in significantly reducing IOP in glaucoma patients with an IOP greater than 30 mmHg.

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0.005%拉坦前列素和0.5%替莫洛尔固定联合应用于眼压大于30mmhg的青光眼患者。

目的:评价0.005%拉坦前列素和0.5%替莫洛尔固定联合治疗IOP≥30mmhg患者的眼压降低效果。设计:前瞻性、随机临床试验。参与者:28例患者。方法:患者既往未接受过青光眼药物治疗。治疗前后进行常规眼科检查和视野测试。结果:治疗前平均眼压为32.28±0.92 mmHg。治疗后第一天的平均IOP水平为18.75 +/- 0.68，第一周为17.96 +/- 0.90，治疗后第一个月为17.64 +/- 0.66。结论:0.005%拉坦前列素和0.5%替莫洛尔的固定组合可显著降低IOP大于30mmhg的青光眼患者的IOP。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical ophthalmology (Auckland, N.Z.)

CiteScore

4.10

自引率

0.00%

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