GlycomicsDB - A Data Integration Platform for Glycans and their Strucutres.

The open medical informatics journal Pub Date : 2011-01-01 Epub Date: 2011-04-19 DOI:10.2174/1874431101105010009
Mahesh Visvanathan, Sasidhar R Siddam, In-Hee Lee, Gerald H Lushington, George R Bousfield
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引用次数: 2

Abstract

Glycomics is a discipline of biology that deals with the structure and function of glycans (or carbohydrates). Analytical techniques such as mass spectrometry (MS) and nuclear magnetic resonance (NMR) are having a significant impact on the field of glycomics. However, effective progress in glycomics research requires collaboration between laboratories to share experimental data, structural information of glycans, and simulation results. Herein we report the development of a web-based data management system that can incorporate large volumes of data from disparate sources and organize them into a uniform format for users to store and access. This system enables participating laboratories to set up a shared data repository which members of interdisciplinary teams can access. The system is able to manage and share raw MS data and structural information of glycans.The database is available at http://www.glycomics.bcf.ku.edu.

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GlycomicsDB -一个聚糖及其结构的数据集成平台。
糖组学是研究聚糖(或碳水化合物)结构和功能的一门生物学学科。质谱(MS)和核磁共振(NMR)等分析技术对糖组学领域产生了重大影响。然而,糖组学研究的有效进展需要实验室之间的合作,共享实验数据、聚糖结构信息和模拟结果。在此,我们报告了基于web的数据管理系统的开发,该系统可以合并来自不同来源的大量数据,并将它们组织成统一的格式供用户存储和访问。该系统使参与的实验室能够建立一个跨学科团队成员可以访问的共享数据存储库。该系统能够管理和共享原始质谱数据和聚糖的结构信息。该数据库可在http://www.glycomics.bcf.ku.edu上获得。
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