Rare case of alimentary butylbiphenyl intoxication.

IF 2 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Journal of applied biomedicine Pub Date : 2022-06-01 Epub Date: 2022-06-10 DOI:10.32725/jab.2022.007
Damian Simcik, Viktor Vorisek, Martin Jakl
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引用次数: 0

Abstract

Background: Unexpected accidental intoxication by uncommon industrial substances is a rare, but challenging and perilous event. To our best knowledge, this is the first reported case of 3,4',5,6'-tetra-tert-butylbiphenyl-2,3'-diol intoxication.

Case report: A 20-year-old man was referred to the Department of Emergency Medicine after seven days of nausea and vomiting triggered by drinking mead. Very high doses of 3,4',5,6'-tetra-tert-butylbiphenyl-2,3'-diol were detected in mead, blood, and urine samples. To prove the intoxication, gas chromatography - ion trap was performed. Symptoms of intoxication persisted for two weeks without significant organ damage. The case report illustrates the need for a multistep approach, focused mainly on the analysis of possible sources of intoxication.

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罕见的消化道丁基联苯中毒病例。
背景:不常见的工业物质意外中毒是一种罕见的,但具有挑战性和危险的事件。据我们所知,这是第一例3,4',5,6'-四叔丁基联苯-2,3'-二醇中毒的报道。病例报告:一名20岁男子因饮用蜂蜜酒引起恶心和呕吐7天后被转介到急诊科。在蜂蜜、血液和尿液样本中检测到非常高剂量的3,4',5,6'-四叔丁基联苯-2,3'-二醇。为证实中毒,采用气相色谱-离子阱法。中毒症状持续了两周,没有明显的器官损害。该病例报告说明需要采取多步骤方法,主要侧重于分析可能的中毒来源。
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来源期刊
Journal of applied biomedicine
Journal of applied biomedicine PHARMACOLOGY & PHARMACY-
CiteScore
2.40
自引率
7.70%
发文量
13
审稿时长
>12 weeks
期刊介绍: Journal of Applied Biomedicine promotes translation of basic biomedical research into clinical investigation, conversion of clinical evidence into practice in all medical fields, and publication of new ideas for conquering human health problems across disciplines. Providing a unique perspective, this international journal publishes peer-reviewed original papers and reviews offering a sensible transfer of basic research to applied clinical medicine. Journal of Applied Biomedicine covers the latest developments in various fields of biomedicine with special attention to cardiology and cardiovascular diseases, genetics, immunology, environmental health, toxicology, neurology and oncology as well as multidisciplinary studies. The views of experts on current advances in nanotechnology and molecular/cell biology will be also considered for publication as long as they have a direct clinical impact on human health. The journal does not accept basic science research or research without significant clinical implications. Manuscripts with innovative ideas and approaches that bridge different fields and show clear perspectives for clinical applications are considered with top priority.
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