Correlation of Walking Activity and Cardiac Hospitalizations in Coronary Patients for 1 Year Post Cardiac Rehabilitation: The More Steps, the Better!

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2022-08-24 eCollection Date: 2022-01-01 DOI:10.1177/11795468221116841
Sinann Al Najem, Andreas Groll, Axel Schmermund, Bernd Nowak, Thomas Voigtländer, Ulrike Kaltenbach, Peter Dohmann, Dietrich Andresen, Jürgen Scharhag
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Abstract

Problem: Reducing risk by improving fitness is one of the main objectives of cardiac rehabilitation (CR). To estimate how the number of steps/day post-CR affects coronary patients' prognosis, we analyzed its correlation with the occurrence of death, hospitalizations, and heart complaints, and if and how other variables (ejection fraction (EF), gender, age) relate to those.

Methods: One hundred eleven patients (male = 91, female = 20; average age ± standard deviation (SD): 61 ± 11 years) who had been in CR due to recent coronary revascularization or chronic coronary syndrome could be enrolled. Patients were advised to document their steps (daily), blood pressure (daily), weight (weekly) and occurrences of a cardiac event in a diary for 1 year post-CR. A Cox proportional hazard model was used to examine the influence of steps/day, EF, gender, and age until the occurrence of an event. Kaplan-Meier curves were generated to compare patients' profiles.

Results: Average steps/day of patients post-CR were 7333 (SD 4426). Increased walking activity reduced risk for cardiac hospitalization (constant steps/day: 5000 vs 7500, hazard rate (HR) reduction of 0.43; 10 000 vs 12 500, HR reduction of 0.20) and risk was higher in patients with an EF < 55% versus EF ⩾ 55% (HR increase of 2.88). Median follow-up time post-CR was 218 days. No patient died, 25 were hospitalized.

Discussion: Monitoring the number of steps of coronary patients post CR could be valuable for estimating patients' prognosis.

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心脏康复后一年内冠心病患者步行活动与心脏病住院的相关性:步数越多越好
问题通过增强体质降低风险是心脏康复(CR)的主要目标之一。为了估计心脏康复后每天的步数对冠心病患者预后的影响,我们分析了步数与死亡、住院和心脏不适发生率的相关性,以及其他变量(射血分数(EF)、性别、年龄)是否与这些因素有关以及如何与这些因素有关:111名因近期冠状动脉血运重建或慢性冠状动脉综合征而处于CR状态的患者(男性91人,女性20人;平均年龄±标准差(SD):61±11岁)被纳入调查范围。建议患者在冠脉再通后的 1 年内记录自己的步数(每天)、血压(每天)、体重(每周)和心脏事件发生情况。采用 Cox 比例危险模型来研究每天步数、EF、性别和年龄对事件发生的影响。生成的 Kaplan-Meier 曲线用于比较患者的情况:结果:CR 后患者的平均步行步数为 7333 步/天(标清 4426 步)。步行活动的增加降低了心脏病住院的风险(恒定步数/天:5000 vs 7500,危险率:0.5%):5000步与7500步相比,危险率(HR)降低了0.43;10 000步与12 500步相比,危险率降低了0.20),EF值较高的患者风险更高:监测冠心病人在 CR 后的行走步数对估计病人的预后很有价值。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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