Acquired Immune Deficiency Syndrome Cholangiopathy: Case Series of Three Patients and Literature Review.

Journal of Medical Cases Pub Date : 2022-09-01 Epub Date: 2022-09-28 DOI:10.14740/jmc3998
Yasir Ahmed, Mustafeez Ur Rahman, Zoia Ehsan Khattak, Jorge Herrera, Eduardo Calderon
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Abstract

Cholangiopathy in acquired immune deficiency syndrome (AIDS) is being less frequently reported since antiretroviral therapy (ART) is available. It is associated with an advanced disease and seen in situations with poor access or non-compliance with ART. Liver biopsy is thought to have low yield in cases of AIDS cholangiopathy, but it can be an important tool in diagnosis, especially early in the course of the disease. The prognosis of AIDS cholangiopathy is generally not favorable, the therapy for opportunistic infections is mostly ineffective and restoration of immune system with ART remains the therapy of choice. We are sharing our experience of diagnosing and managing three cases of AIDS cholangiopathy.

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获得性免疫缺陷综合征胆管病:3例病例分析及文献复习。
自抗逆转录病毒治疗(ART)可用以来,获得性免疫缺陷综合征(艾滋病)的胆管病报道较少。它与疾病晚期有关,见于难以获得抗逆转录病毒治疗或不遵守抗逆转录病毒治疗的情况。肝活检被认为在艾滋病胆管病的病例中成功率低,但它可以是诊断的重要工具,特别是在疾病的早期。艾滋病胆管病的预后通常不佳,机会性感染的治疗大多无效,抗逆转录病毒治疗仍然是免疫系统恢复的首选治疗方法。我们将分享我们诊断和治疗三例艾滋病胆管病的经验。
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