Transient Pneumonitis as a Possible Adverse Reaction to the BNT162b2 COVID-19 mRNA Vaccine in a Patient with Rheumatoid Arthritis: A Case Report and Review of the Literature.

Case Reports in Rheumatology Pub Date : 2022-08-23 eCollection Date: 2022-01-01 DOI:10.1155/2022/3124887
Yusuke Ohkubo, Shin-Ichiro Ohmura, Ryuhei Ishihara, Toshiaki Miyamoto
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Abstract

The coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 has led to rapid progress in vaccine development to prevent the spread of the disease. Although COVID-19 vaccines have excellent effectiveness in reducing morbidity and disease severity with minor adverse reactions, some patients develop late hypersensitivity events as autoimmune reactions such as rheumatoid arthritis, lupus nephritis, and vasculitis following COVID-19 vaccination. Herein, we describe a case of pneumonitis following COVID-19 mRNA vaccination in a patient with rheumatoid arthritis, which resolved spontaneously.

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类风湿性关节炎患者短暂性肺炎可能是BNT162b2 COVID-19 mRNA疫苗的不良反应:1例报告和文献综述
由严重急性呼吸综合征冠状病毒2型引起的冠状病毒病(COVID-19)大流行导致预防该疾病传播的疫苗开发取得了快速进展。尽管COVID-19疫苗在降低发病率和疾病严重程度方面具有出色的有效性,且不良反应较小,但一些患者在接种COVID-19疫苗后出现晚期超敏反应,如类风湿关节炎、狼疮性肾炎和血管炎。在此,我们描述了一例类风湿关节炎患者在接种COVID-19 mRNA疫苗后出现肺炎的病例,该病例自行消退。
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12 weeks
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