Dissociation and misdiagnosis of schizophrenia in populations experiencing chronic discrimination and social defeat.

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-05-01 Epub Date: 2022-09-05 DOI:10.1080/15299732.2022.2120154
Heather Hall
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引用次数: 0

Abstract

As recently as the late 20th century, Schizophrenia, a category of mental illness with widely varying phenotypic symptoms, was believed by psychobiologists to be a genetically based disorder in which the environment played a limited etiological role. Yet a growing body of evidence indicates a strong correlation between schizophrenia and environmental factors. This theoretical paper explores the relationship between highly elevated rates of schizophrenia in some low-income minority communities worldwide and trauma-related dissociative symptoms that often mimic schizophrenia. Elevated rates of schizophrenia in racially and ethnically isolated, inner-city Black populations are well documented. This paper contains evidence proposing that this amplification in the rate of schizophrenia is mediated by childhood trauma, disorganized attachment, and social defeat. Further, evidence demonstrating how these three variables combine in early childhood to incubate dissociative disorders will also be conveyed. The misdiagnosis of dissociative disorders as schizophrenia is theorized to partially mediate the increased rate of schizophrenia in communities that experience high levels of racial/ethnic discrimination. It is argued that this misdiagnosis is often attributable to cultural misunderstanding and/or a lack of knowledge about dissociative disorders.

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长期遭受歧视和社会挫折的人群中精神分裂症的分离和误诊。
精神分裂症是一种表型症状千差万别的精神疾病,早在 20 世纪末,心理生物学家就认为精神分裂症是一种以基因为基础的疾病,环境在其中发挥的致病作用有限。然而,越来越多的证据表明,精神分裂症与环境因素密切相关。这篇理论性论文探讨了世界上一些低收入少数民族社区精神分裂症发病率极高与经常模仿精神分裂症的创伤相关分离症状之间的关系。在种族和民族隔绝的内城黑人群体中,精神分裂症发病率的升高是有据可查的。本文提供的证据表明,精神分裂症发病率的升高是由童年创伤、无序的依恋关系和社会挫败感引起的。此外,本文还将提供证据,证明这三个变量如何在童年早期结合起来,诱发分离性障碍。解离性障碍被误诊为精神分裂症的部分原因是,在种族/民族歧视严重的社区,精神分裂症的发病率有所上升。有观点认为,这种误诊通常可归因于文化误解和/或对分离障碍缺乏了解。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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