Spontaneous Acute Mesenteric Thrombosis in a Patient With Hemoglobin E Thalassemia.

Journal of Medical Cases Pub Date : 2022-08-01 Epub Date: 2022-08-19 DOI:10.14740/jmc3969
Joseph Asemota, Ademola S Ojo, Somtochukwu G Ojukwu, Mohammed Saleh, Ravi Sarma
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Abstract

Acute mesenteric vein thrombosis (MVT) is an uncommon cause of mesenteric ischemia and portal hypertension. The common risk factors for the development of MVT include surgery, acute-intraabdominal inflammatory disorders, malignancies, and other prothrombotic states. However, MVT can occur in the absence of these risk factors. We describe the case of a 40-year-old man with a new diagnosis of hemoglobin E thalassemia and MVT and discuss the relationship between the hemoglobinopathy and thrombosis based on evidence from existing literature. The case emphasizes the importance of a high index of suspicion in the diagnosis of MVT in other to reduce complications and improve overall outcomes.

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地中海血红蛋白E贫血患者自发性急性肠系膜血栓形成。
急性肠系膜静脉血栓形成(MVT)是一种罕见的肠系膜缺血和门静脉高压的原因。发生MVT的常见危险因素包括手术、急性腹内炎性疾病、恶性肿瘤和其他血栓形成前状态。然而,在没有这些危险因素的情况下,MVT也可能发生。我们报告一名40岁男性新诊断为血红蛋白E地中海贫血和MVT的病例,并根据现有文献的证据讨论血红蛋白病与血栓形成的关系。该病例强调了在其他MVT诊断中高度怀疑的重要性,以减少并发症和改善总体结果。
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