Optimizing low contrast volume thoracic CT angiography: From the basics to the advanced.

IF 18 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2022-07-29 eCollection Date: 2022-01-01 DOI:10.25259/JCIS_51_2022

Katherine Kaproth-Joslin, Susan Hobbs, Prabhakar Rajiah, Apeksha Chaturvedi, Abhishek Chaturvedi

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Abstract

Contrast-enhanced CT angiography (CTA) is a widely used, noninvasive imaging technique for evaluating cardiovascular structures. Contrast-induced nephrotoxicity is a concern in renal disease; however, the true nephrotoxic potential of iodinated contrast media (CM) is unknown. If a renal impaired patient requires CTA, it is important to protect the kidneys from further harm by reducing total iodinated CM volume while still obtaining diagnostic quality imaging. These same reduced volume CM techniques can also be applied to nonrenal impaired patients in times of CM shortage. This educational review discusses several modifications to CTA that can be adapted to both conventional 64-slice and the newer generation CT scanners which enable subsecond acquisition with a reduced CM volume technique. Such modifications include hardware and software adjustments and changes to both the volume and flow rate of administered CM, with the goal to reduce the dose of CM without compromising diagnostic yield.

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优化低造影剂量胸部 CT 血管造影：从基础到高级。

对比度增强 CT 血管造影术 (CTA) 是一种广泛使用的评估心血管结构的无创成像技术。造影剂引起的肾毒性是肾病患者的一个担忧；然而，碘化造影剂 (CM) 的真正肾毒性尚不清楚。如果肾功能受损的患者需要进行 CTA，则必须通过减少碘化造影剂的总用量来保护肾脏免受进一步伤害，同时还能获得高质量的成像诊断。在 CM 短缺时，这些减少 CM 容量的技术同样适用于非肾功能受损患者。本教育综述讨论了对 CTA 进行的几项修改，这些修改可适用于传统的 64 片 CT 扫描仪和新一代 CT 扫描仪，它们可通过减少 CM 容量技术实现亚秒采集。这些修改包括硬件和软件调整，以及改变给药 CM 的容量和流速，目的是在不影响诊断结果的情况下减少 CM 的剂量。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.