Systematic review of exercise therapy in the management of post-thrombotic syndrome.

IF 17.7 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2022-12-01 Epub Date: 2022-09-26 DOI:10.1177/02683555221129738

Sara Jasionowska, Benedict R H Turner, Matthew Machin, Sarah Onida, Adam M Gwozdz, Joseph Shalhoub, Alun H Davies

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Abstract

Objectives: Exercise improves haemodynamic parameters in patients with chronic venous disease. There is a paucity of evidence on its effect in post-thrombotic syndrome (PTS). The aim of this systematic review is to assess the impact of exercise in PTS.

Methods: Adhering to PRISMA guidelines and following PROSPERO registration (CRD42021220924), MEDLINE, Cochrane Library, EMBASE database, and trial registries were searched on 19th May 2022.

Results: One article met the inclusion criteria and a narrative synthesis was carried out. The included randomised controlled trial reported a between-group mean difference of 4.6 points (p = .027) in the VEINES-QOL score and -2.0 points (p = .14) in the Villalta score, in favour of exercise therapy. The statistical significance threshold was not reached.

Conclusion: Data on exercise in PTS remains sparse but exercise appears to be a safe intervention. In the context of this literature, a potential future trial and outcome reporting measures are suggested.

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运动疗法治疗血栓后综合征的系统综述。

目标：运动可改善慢性静脉疾病患者的血流动力学参数。关于运动对血栓后综合征（PTS）的影响，目前还缺乏相关证据。本系统综述旨在评估运动对 PTS 的影响：方法：2022 年 5 月 19 日，根据 PRISMA 指南和 PROSPERO 注册（CRD42021220924），检索了 MEDLINE、Cochrane 图书馆、EMBASE 数据库和试验登记处：结果：有一篇文章符合纳入标准，并进行了叙述性综合。纳入的随机对照试验报告显示，运动疗法在VEINES-QOL评分和Villalta评分中的组间平均差异分别为4.6分（p = .027）和-2.0分（p = .14）。未达到统计学显著性临界值：结论：有关运动治疗 PTS 的数据仍然很少，但运动似乎是一种安全的干预措施。根据这些文献，我们建议未来可能进行的试验和结果报告措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.