Predictive factors associated with successful response to utrasound guided genicular radiofrequency ablation.

IF 3.4 3区 医学 Q2 CLINICAL NEUROLOGY Korean Journal of Pain Pub Date : 2022-10-01 DOI:10.3344/kjp.2022.35.4.447
Selin Guven Kose, Halil Cihan Kose, Feyza Celikel, Omer Taylan Akkaya
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引用次数: 10

Abstract

Background: Ultrasound-guided genicular nerve radiofrequency (RF) procedures are of interest in the management of chronic knee pain. A wide variety of demographic, clinical, and procedural characteristics can affect treatment success. This study aimed to determine predictive factors to provide superior treatment outcomes.

Methods: The demographic, clinical, and technical data of patients who received genicular nerve RF for knee pain between September 2016 and September 2021 were evaluated. A positive outcome was defined as at least 50% pain relief on a pain score for at least 6 months. Logistic regression analysis was performed to determine the factors associated with a successful response to genicular RF.

Results: Among 206 patients who underwent genicular RF, 62% of the patients reported successful outcomes at 6 months. In the multivariate model, targeting 5 nerves (odds ratio [OR], 6.184; 95% confidence interval [CI], 2.291-16.690; P < 0.001) was the most significant predictor of successful outcomes. Multivariable logistic regression analysis showed that prognostic genicular nerve block with a 50% cut-off value (OR, 2.109; 95% CI, 1.038-4.287; P = 0.039), no opioid use (OR, 2.753; 95% CI, 1.405-5.393; P = 0.003), and depression (OR, 0.297; 95% CI, 0.124-0.713; P = 0.007) were the predictive factors significantly associated with response to genicular RF.

Conclusions: Clinical and technical factors associated with better treatment outcomes were ultimately targeting more nerves, performing prognostic block, no opioid use, and no depression. These results are expected to be considered when selecting patients for genicular RF.

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超声引导下膝关节射频消融术成功应答的预测因素。
背景:超声引导下膝神经射频(RF)手术对慢性膝关节疼痛的治疗很有意义。各种各样的人口统计学、临床和程序特征都会影响治疗的成功。本研究旨在确定预测因素以提供更好的治疗结果。方法:对2016年9月至2021年9月期间接受膝神经射频治疗的膝关节疼痛患者的人口学、临床和技术资料进行评估。阳性结果定义为疼痛评分至少缓解50%,持续至少6个月。进行逻辑回归分析以确定与遗传RF成功应答相关的因素。结果:在206例接受膝关节射频治疗的患者中,62%的患者在6个月时报告了成功的结果。在多变量模型中,针对5个神经(优势比[OR], 6.184;95%置信区间[CI], 2.291-16.690;P < 0.001)是成功预后的最显著预测因子。多变量logistic回归分析显示膝关节神经阻滞的预后截断值为50% (OR, 2.109;95% ci, 1.038-4.287;P = 0.039),无阿片类药物使用(OR, 2.753;95% ci, 1.405-5.393;P = 0.003),抑郁(OR, 0.297;95% ci, 0.124-0.713;P = 0.007)是与膝关节射频治疗反应显著相关的预测因素。结论:与更好的治疗结果相关的临床和技术因素最终是针对更多的神经,进行预后阻断,不使用阿片类药物,没有抑郁。在选择患者进行膝性射频治疗时应考虑这些结果。
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来源期刊
Korean Journal of Pain
Korean Journal of Pain Medicine-Anesthesiology and Pain Medicine
CiteScore
5.40
自引率
7.10%
发文量
57
审稿时长
16 weeks
期刊介绍: Korean Journal of Pain (Korean J Pain, KJP) is the official journal of the Korean Pain Society, founded in 1986. It has been published since 1988. It publishes peer reviewed original articles related to all aspects of pain, including clinical and basic research, patient care, education, and health policy. It has been published quarterly in English since 2009 (on the first day of January, April, July, and October). In addition, it has also become the official journal of the International Spinal Pain Society since 2016. The mission of the Journal is to improve the care of patients in pain by providing a forum for clinical researchers, basic scientists, clinicians, and other health professionals. The circulation number per issue is 50.
期刊最新文献
Ultrasound-guided pain management: pros, cons, and benefits for the Philippines. Retraction: Comparison of the efficacy of genicular nerve phenol neurolysis and radiofrequency ablation for pain management in patients with knee osteoarthritis. A critical factor in resistant piriformis syndrome cases: awareness of sacrotuberous ligament pain. Effect of ultrasound-guided ilioinguinal-iliohypogastric nerve block on chronic pain in patients undergoing open inguinal hernia surgery under spinal anesthesia: a randomized double-blind study. Ultrasound-guided transoral pterygopalatine fossa block: cadaveric elaboration of a novel technique.
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