Adult diffuse hepatic hemangiomatosis.

Q4 Medicine Autopsy and Case Reports Pub Date : 2022-09-23 eCollection Date: 2022-01-01 DOI:10.4322/acr.2021.401
Neha Bhardwaj, Mayur Parkhi, Manish Kumar, Lileswar Kaman, Suvradeep Mitra
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引用次数: 1

Abstract

Diffuse hepatic hemangiomatosis (DHH) is an uncommon vascular lesion, though hemangiomas are the commonest benign tumors of the liver. The etiology is largely unknown to date; however, its association with giant cavernous hemangiomas (GCH) has been reported in the literature. We present herein, the case of a 37-year-old hypothyroid woman with abdominal fullness for 2 months. The contrast-enhanced computed tomography revealed multiple well-encapsulated lesions involving the liver lobes and was diagnosed as giant cavernous hemangiomas. Most of them, except the deep-seated ones, were enucleated. Histopathological examination highlighted the presence of GCH with irregular margin, replacement of hepatic parenchyma, and presence of multiple micro-hemangiomas suggesting the possibility of DHH further substantiated by retrospective radiological assessment. No extrahepatic vascular lesion was noted, and the post-operative recovery and follow-up were uneventful. Adult DHH is an uncommon entity. The diagnosis of DHH and its distinction from GCH are important from the management and prognostic point of view as recurrence, extrahepatic manifestations, features of consumption coagulopathy, and death from the complications are not uncommon.

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成人弥漫性肝血管瘤病。
尽管肝血管瘤是肝脏最常见的良性肿瘤,但弥漫性肝血管瘤病(DHH)是一种罕见的血管病变。病因至今仍不清楚;然而,其与巨海绵状血管瘤(GCH)的关联已在文献中报道。我们在此报告一位37岁甲状腺功能减退的女性,腹部充盈2个月。增强计算机断层扫描显示多个包膜良好的病变累及肝叶,诊断为巨大海绵状血管瘤。除了那些根深蒂固的,大多数都是去核的。组织病理学检查显示GCH边缘不规则,肝实质替代,存在多个微血管瘤,提示DHH的可能性,回顾性影像学评估进一步证实。未发现肝外血管病变,术后恢复和随访顺利。成人DHH是一种罕见的疾病。从治疗和预后的角度来看,DHH的诊断及其与GCH的区别是重要的,因为复发、肝外表现、消耗性凝血功能障碍的特征以及并发症导致的死亡并不罕见。
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来源期刊
Autopsy and Case Reports
Autopsy and Case Reports Medicine-Internal Medicine
CiteScore
1.20
自引率
0.00%
发文量
60
审稿时长
9 weeks
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