Viral inactivation by light.

IF 27.2 Q1 OPTICS eLight Pub Date : 2022-01-01 Epub Date: 2022-09-26 DOI:10.1186/s43593-022-00029-9
Mohammad Sadraeian, Le Zhang, Farzaneh Aavani, Esmaeil Biazar, Dayong Jin
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引用次数: 14

Abstract

Nowadays, viral infections are one of the greatest challenges for medical sciences and human society. While antiviral compounds and chemical inactivation remain inadequate, physical approaches based on irradiation provide new potentials for prevention and treatment of viral infections, without the risk of drug resistance and other unwanted side effects. Light across the electromagnetic spectrum can inactivate the virions using ionizing and non-ionizing radiations. This review highlights the anti-viral utility of radiant methods from the aspects of ionizing radiation, including high energy ultraviolet, gamma ray, X-ray, and neutron, and non-ionizing photo-inactivation, including lasers and blue light.

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光灭活病毒。
如今,病毒感染是医学和人类社会面临的最大挑战之一。虽然抗病毒化合物和化学灭活仍然不足,但基于辐射的物理方法为预防和治疗病毒感染提供了新的潜力,而没有耐药性和其他不必要的副作用的风险。电磁波谱上的光可以通过电离和非电离辐射使病毒粒子失活。这篇综述从电离辐射(包括高能紫外线、伽马射线、X射线和中子)和非电离光灭活(包括激光和蓝光)方面强调了辐射方法的抗病毒效用。
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CiteScore
30.40
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