Delayed urticaria after BNT162b2 booster vaccination at previous intradermal test site with severe acute respiratory syndrome-coronavirus-2 spike protein.

IF 1.6 Q3 ALLERGY Asia Pacific Allergy Pub Date : 2022-07-18 eCollection Date: 2022-07-01 DOI:10.5415/apallergy.2022.12.e27
Jidapa Triwatcharikorn, Jettanong Klaewsongkram, Pawinee Rerknimitr
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引用次数: 1

Abstract

Urticaria is a common cutaneous adverse event from coronavirus disease 2019 vaccination. Previous studies hypothesized that excipients as polyethylene glycol in BNT162b2 vaccine and polysorbate in ChAdOx1 nCoV-19 vaccine are allergens. A 28-year-old woman had urticaria after a booster vaccination with BNT162b2 at the site of previous intradermal injection with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) spike protein. This reaction emphasized that delayed urticaria may not be an allergic reaction to excipient but rather to the immunogen as such as SARS-CoV-2 spike protein.

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严重急性呼吸综合征-冠状病毒-2刺突蛋白在先前皮内试验点接种BNT162b2加强疫苗后出现延迟性荨麻疹。
荨麻疹是2019冠状病毒病疫苗接种后常见的皮肤不良事件。先前的研究假设赋形剂如BNT162b2疫苗中的聚乙二醇和ChAdOx1 nCoV-19疫苗中的聚山梨酯是过敏原。一名28岁妇女在先前皮内注射严重急性呼吸综合征-冠状病毒-2 (SARS-CoV-2)刺突蛋白的部位加强接种BNT162b2后出现荨麻疹。这一反应强调了延迟性荨麻疹可能不是对赋形剂的过敏反应,而是对SARS-CoV-2刺突蛋白等免疫原的过敏反应。
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来源期刊
CiteScore
2.50
自引率
5.90%
发文量
33
期刊介绍: Asia Pacific Allergy (AP Allergy) is the official journal of the Asia Pacific Association of Allergy, Asthma and Clinical Immunology (APAAACI). Although the primary aim of the journal is to promote communication between Asia Pacific scientists who are interested in allergy, asthma, and clinical immunology including immunodeficiency, the journal is intended to be available worldwide. To enable scientists and clinicians from emerging societies appreciate the scope and intent of the journal, early issues will contain more educational review material. For better communication and understanding, it will include rational concepts related to the diagnosis and management of asthma and other immunological conditions. Over time, the journal will increase the number of original research papers to become the foremost citation journal for allergy and clinical immunology information of the Asia Pacific in the future.
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