Weight stability in adults with obesity initiating medical marijuana treatment for other medical conditions.

Michelle R Lent, Meghan Visek, Paulina Syracuse, Karen L Dugosh, David S Festinger
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Abstract

Few studies have evaluated weight change in patients who initiate medical marijuana treatment to address diagnosed health concerns. The objective of this study was to examine whether patients initiating medical marijuana use for a qualifying health condition experienced changes in health and biopsychosocial functioning over time, including weight gain or loss. Specifically, this observational, longitudinal study evaluated changes in the body mass index (BMI) of adults with co-morbid obesity (body mass index [BMI] ≥ 30 kg/m2) and severe obesity (BMI ≥ 40 kg/m2) who were starting medical marijuana treatment for any of the 23 qualifying medical conditions at one of three dispensaries in Pennsylvania. Height and weight measurements were collected at baseline (prior to medical marijuana use) and then 90 days (± 14 days) later. Participants included in analyses (n = 52, M = 55.0 ± 13.6 years, 59.6% female) had a mean baseline BMI of 36.2 ± 5.4 kg/m2 and the majority sought medical marijuana for chronic pain (73.1%). No significant change in BMI was observed from baseline to month three (p > 0.05) in the sample. Additionally, no significant change in BMI was observed in the subset of patients with severe obesity (n = 12, p > 0.05). Our findings are limited by low follow-up rates and convenience sampling methodology but may help to mitigate weight gain concerns in the context of medical marijuana use.

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成人肥胖患者开始使用医用大麻治疗其他疾病的体重稳定性
很少有研究评估开始使用医用大麻治疗以解决诊断出的健康问题的患者的体重变化。本研究的目的是检查患者在符合条件的健康状况下开始使用医用大麻是否会随着时间的推移在健康和生物心理社会功能方面发生变化,包括体重增加或减少。具体来说,这项观察性纵向研究评估了在宾夕法尼亚州三家药房之一的23种符合条件的医疗条件中开始接受医用大麻治疗的成人共病肥胖(体重指数[BMI]≥30 kg/m2)和严重肥胖(BMI≥40 kg/m2)的体重指数(BMI)的变化。在基线(医用大麻使用前)和90天(±14天)后收集身高和体重测量。纳入分析的参与者(n = 52, M = 55.0±13.6岁,59.6%为女性)的平均基线BMI为36.2±5.4 kg/m2,大多数(73.1%)寻求医用大麻治疗慢性疼痛。从基线到第3个月,样本中BMI无显著变化(p > 0.05)。此外,重度肥胖患者亚组BMI无显著变化(n = 12, p > 0.05)。我们的研究结果受到低随访率和方便抽样方法的限制,但可能有助于减轻医用大麻使用背景下体重增加的担忧。
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