What psammoma bodies can represent in the thyroid. What we recently learnt from a story of lack of evidence.

IF 4.4 Q1 PATHOLOGY PATHOLOGICA Pub Date : 2022-10-01 DOI:10.32074/1591-951X-815
Lina Cardisciani, Federica Policardo, Pietro Tralongo, Vincenzo Fiorentino, Esther Diana Rossi
{"title":"What psammoma bodies can represent in the thyroid. What we recently learnt from a story of lack of evidence.","authors":"Lina Cardisciani,&nbsp;Federica Policardo,&nbsp;Pietro Tralongo,&nbsp;Vincenzo Fiorentino,&nbsp;Esther Diana Rossi","doi":"10.32074/1591-951X-815","DOIUrl":null,"url":null,"abstract":"<p><p>The detection of psammoma bodies (PBs) in the thyroid gland is commonly associated to classic papillary thyroid carcinoma (PTC) and are frequently encountered in differnt subtypes of PTCs. Nonetheless, the evidence of PBs without a PTC may represent a diagnostic challenge. The general statement is that PBs represent a metastatic finding of PTC either when encountered inside the thyroid parenchyma or in the perithyroidal lymph nodes. The majority of authors assess that in presence of PBs, a search for an occult PTC is strongly encouraged and mandatory, especially if a lobectomy had been performed. In fact, it is not uncommon that a contralateral or ipsilateral tumor, mostly PTC, is found leading to the suggestion that the best recommendation is to submit the entire thyroid tissue. Nonetheless, when a cancer has not been found, the possibility of the rare evenience that PBs are likely to be associated with benign conditions should be considered among the differential diagnosis. Herein a short commentary and review of the literature on PBs detection and its diagnosis, based on our recent experience.</p>","PeriodicalId":45893,"journal":{"name":"PATHOLOGICA","volume":null,"pages":null},"PeriodicalIF":4.4000,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/01/7c/pathol-2022-05-373.PMC9614304.pdf","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"PATHOLOGICA","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32074/1591-951X-815","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PATHOLOGY","Score":null,"Total":0}
引用次数: 3

Abstract

The detection of psammoma bodies (PBs) in the thyroid gland is commonly associated to classic papillary thyroid carcinoma (PTC) and are frequently encountered in differnt subtypes of PTCs. Nonetheless, the evidence of PBs without a PTC may represent a diagnostic challenge. The general statement is that PBs represent a metastatic finding of PTC either when encountered inside the thyroid parenchyma or in the perithyroidal lymph nodes. The majority of authors assess that in presence of PBs, a search for an occult PTC is strongly encouraged and mandatory, especially if a lobectomy had been performed. In fact, it is not uncommon that a contralateral or ipsilateral tumor, mostly PTC, is found leading to the suggestion that the best recommendation is to submit the entire thyroid tissue. Nonetheless, when a cancer has not been found, the possibility of the rare evenience that PBs are likely to be associated with benign conditions should be considered among the differential diagnosis. Herein a short commentary and review of the literature on PBs detection and its diagnosis, based on our recent experience.

Abstract Image

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
沙粒体在甲状腺中的表现。我们最近从一个缺乏证据的故事中学到了什么。
甲状腺沙粒小体(PBs)的检测通常与典型的甲状腺乳头状癌(PTC)相关,并且经常出现在不同亚型的PTC中。尽管如此,无PTC的PBs证据可能是一种诊断挑战。一般的说法是,当遇到甲状腺实质内或甲状腺周围淋巴结时,PBs代表PTC的转移发现。大多数作者评估,在PBs存在的情况下,强烈鼓励和强制搜索隐匿性PTC,特别是如果已经进行了肺叶切除术。事实上,发现对侧或同侧肿瘤(主要是PTC)并不罕见,因此建议最好的建议是提交整个甲状腺组织。尽管如此,当尚未发现癌症时,在鉴别诊断中应考虑PBs可能与良性疾病相关的罕见可能性。本文根据我们最近的经验,对PBs检测及其诊断的文献进行简短的评论和回顾。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
PATHOLOGICA
PATHOLOGICA PATHOLOGY-
CiteScore
5.90
自引率
5.70%
发文量
108
期刊最新文献
A case series of chorioangiomas in placentas with clinical indication for histological examination. A preliminary study on the diagnostic performance of the uPath PD-L1 (SP263) artificial intelligence (AI) algorithm in patients with NSCLC treated with PD-1/PD-L1 checkpoint blockade. Asbestos exposure diagnosis in pulmonary tissues. Colitis cystica profunda associated with diverticulosis and calcification mimicking colorectal carcinoma: a case report and a brief literature review. Digital transition in pathology lab: a survey from the Lombardy region.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1