Primary intraosseous solitary fibrous tumor: an extremely rare case report and brief review of the literature.

IF 4.4 Q1 PATHOLOGY PATHOLOGICA Pub Date : 2022-10-01 DOI:10.32074/1591-951X-524
Giulia Coppola, Carmine Zoccali, Jacopo Baldi, Alessio Annovazzi, Thedora Daralioti, Mariavittoria Vescovo, Renato Covello
{"title":"Primary intraosseous solitary fibrous tumor: an extremely rare case report and brief review of the literature.","authors":"Giulia Coppola,&nbsp;Carmine Zoccali,&nbsp;Jacopo Baldi,&nbsp;Alessio Annovazzi,&nbsp;Thedora Daralioti,&nbsp;Mariavittoria Vescovo,&nbsp;Renato Covello","doi":"10.32074/1591-951X-524","DOIUrl":null,"url":null,"abstract":"<p><p>Solitary fibrous tumor (SFT), a rare mesenchymal neoplasm of fibroblastic origin, was initially discovered in the mediastinal pleura and then described in many extra-pleural sites.</p><p><p>The reports of primary solitary fibrous tumor of bone are extremely rare and only a few cases have been previously mentioned in the literature, most of which in flat and short bones.</p><p><p>Here we present the case of a 53-year-old female, who was referred to the emergency department of a peripheral hospital after an accidental fall. Imaging studies revealed an intertrochanteric fracture with an underlying intramedullary lytic lesion. A biopsy was performed and a diagnosis of Ewing sarcoma was initially suggested. She arrived at our hospital where we reevaluated the case. The biopsy was reviewed and a diagnosis of intraosseous SFT was proposed. She underwent en-block resection of the proximal right femur.</p><p><p>Primary SFTs of the bone are, like in our case, easily misdiagnosed due to the low specificity of the imaging studies and the extreme rarity of the localization. An accurate diagnosis and early resection are very important and with careful long-term follow-up is essential, particularly in those who with malignant behavior, for the early detection of possible recurrence or metastasis.</p>","PeriodicalId":45893,"journal":{"name":"PATHOLOGICA","volume":null,"pages":null},"PeriodicalIF":4.4000,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/df/f0/pathol-2022-05-376.PMC9614297.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"PATHOLOGICA","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32074/1591-951X-524","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PATHOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Solitary fibrous tumor (SFT), a rare mesenchymal neoplasm of fibroblastic origin, was initially discovered in the mediastinal pleura and then described in many extra-pleural sites.

The reports of primary solitary fibrous tumor of bone are extremely rare and only a few cases have been previously mentioned in the literature, most of which in flat and short bones.

Here we present the case of a 53-year-old female, who was referred to the emergency department of a peripheral hospital after an accidental fall. Imaging studies revealed an intertrochanteric fracture with an underlying intramedullary lytic lesion. A biopsy was performed and a diagnosis of Ewing sarcoma was initially suggested. She arrived at our hospital where we reevaluated the case. The biopsy was reviewed and a diagnosis of intraosseous SFT was proposed. She underwent en-block resection of the proximal right femur.

Primary SFTs of the bone are, like in our case, easily misdiagnosed due to the low specificity of the imaging studies and the extreme rarity of the localization. An accurate diagnosis and early resection are very important and with careful long-term follow-up is essential, particularly in those who with malignant behavior, for the early detection of possible recurrence or metastasis.

Abstract Image

Abstract Image

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
原发性骨内孤立性纤维性肿瘤:一例极为罕见的病例报告及文献回顾。
孤立性纤维性肿瘤(SFT)是一种罕见的纤维母细胞间质肿瘤,最初发现于纵隔胸膜,后来在许多胸膜外部位也有报道。原发性骨孤立性纤维性肿瘤的报道极为罕见,文献中只报道过少数病例,且多发生在扁平骨和短骨。在这里,我们提出的情况下,53岁的女性,谁被转介到急诊室的外围医院意外跌倒后。影像学检查显示转子间骨折伴潜在髓内溶解性病变。活检后初步诊断为尤文氏肉瘤。她来到我们医院,我们重新评估了这个病例。我们回顾了活检并提出了骨内SFT的诊断。她接受了右股骨近端整块切除。像我们的病例一样,由于影像学研究的低特异性和定位的极端罕见,原发性骨SFTs很容易被误诊。准确的诊断和早期切除是非常重要的,仔细的长期随访是必不可少的,特别是对于那些有恶性行为的患者,早期发现可能的复发或转移。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
PATHOLOGICA
PATHOLOGICA PATHOLOGY-
CiteScore
5.90
自引率
5.70%
发文量
108
期刊最新文献
A case series of chorioangiomas in placentas with clinical indication for histological examination. A preliminary study on the diagnostic performance of the uPath PD-L1 (SP263) artificial intelligence (AI) algorithm in patients with NSCLC treated with PD-1/PD-L1 checkpoint blockade. Asbestos exposure diagnosis in pulmonary tissues. Colitis cystica profunda associated with diverticulosis and calcification mimicking colorectal carcinoma: a case report and a brief literature review. Digital transition in pathology lab: a survey from the Lombardy region.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1